Dynorphin B (trifluoroacetate salt)

Dynorphin B is a 13-residue opioid peptide released from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as a kappa1b-opioid receptor agonist (Ki = 1.1 nM) and has been implicated in antinociceptive functions. Dynorphin B has also been used to prime cardiogenesis in pluripotent embryonic stem cells.Formal Name: dynorphin B (swine), trifluoroacetate salt. Synonyms: Dynorphin B-13, Rimorphin. Molecular Formula: C74H115N21O17 . XCF3COOH. Formula Weight: 1570.8. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, PBS (pH 7.2): 5 mg/ml. lambdamax: 278 nm. SMILES: O=C([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](NC(CNC(CNC([C@@H](N)CC1=CC=C(O)C=C1)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)N[C@H](C(N[C@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@H](C(O)=O)[C@H](O)C)=O)=O)=O)=O)CC3=CC=CC=C3.O=C(O)C(F)(F)F. InChi Code: InChI=1S/C74H115N21O17.C2HF3O2/c1-40(2)34-53(91-68(107)54(36-44-18-10-8-11-19-44)86-58(100)39-84-57(99)38-85-62(101)48(76)35-46-25-27-47(97)28-26-46)67(106)89-51(24-17-33-83-74(80)81)63(102)87-50(23-16-32-82-73(78)79)64(103)90-52(29-30-56(77)98)65(104)92-55(37-45-20-12-9-13-21-45)69(108)88-49(22-14-15-31-75)66(105)93-59(41(3)4)70(109)94-60(42(5)6)71(110)95-61(43(7)96)72(111)112,3-2(4,5)1(6)7/h8-13,18-21,25-28,40-43,48-55,59-61,96-97H,14-17,22-24,29-39,75-76H2,1-7H3,(H2,77,98)(H,84,99)(H,85,101)(H,86,100)(H,87,102)(H,88,108)(H,89,106)(H,90,103)(H,91,107)(H,92,104)(H,93,105)(H,94,109)(H,95,110)(H,111,112)(H4,78,79,82)(H4,80,81,83),(H,6,7)/t43-,48+,49-,50+,51+,52+,53+,54+,55+,59+,60+,61+,/m1./s1. InChi Key: LRQRGJLZDSMZAB-KPJVINDFSA-N.