DC-2 Peptide (trifluoroacetate salt)

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Item number	Size	Manual	Delivery time	Price
Cay45287-1	1 mg	-	6 - 10 business days*	69.00€
Cay45287-5	5 mg	-	6 - 10 business days*	308.00€
Cay45287-10	10 mg	-	6 - 10 business days*	545.00€
Cay45287-25	25 mg	-	6 - 10 business days*	1,106.00€

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DC-2 peptide is a synthetic peptide that contains a DHHC palmitoylation motif. It reduces H-Ras... more

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Product information "DC-2 Peptide (trifluoroacetate salt)"

DC-2 peptide is a synthetic peptide that contains a DHHC palmitoylation motif. It reduces H-Ras cell membrane localization in HeLa cells and increases ERK and Akt phosphorylation in SW480 colorectal cancer cells with high EGFR expression but not in SW620 colorectal cancer cells with low EGFR expression. DC-2 reduces viability of HeLa and MDA-MB-231 breast cancer cells at concentrations ranging from 20 to 100 µM. SMILES: [H]NCC(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(N)=O)CC2=CNC3=C2C=CC=C3)=O)=O)CS)=O)CC4=CN=CN4)=O)CC5=CN=CN5)=O)CC(O)=O)=O)CCSC)=O)=O)=O)=O)=O)CC6=CC=CC=C6)=O)=O)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F. InChi Code: InChI=1S/C115H189N43O23S2.C2HF3O2/c1-63(2)48-81(140-91(160)56-120)103(173)146-75(32-19-42-133-112(123)124)97(167)142-71(28-11-15-38-116)94(164)144-77(34-21-44-135-114(127)128)100(170)151-82(49-64(3)4)104(174)147-76(33-20-43-134-113(125)126)98(168)143-74(31-14-18-41-119)99(169)152-83(50-65-24-7-6-8-25-65)105(175)148-78(35-22-45-136-115(129)130)101(171)155-86(54-90(121)159)108(178)145-73(30-13-17-40-118)95(165)141-72(29-12-16-39-117)96(166)149-79(37-47-183-5)102(172)156-87(55-92(161)162)109(179)154-84(52-67-58-131-61-138-67)106(176)153-85(53-68-59-132-62-139-68)107(177)157-88(60-182)111(181)158-46-23-36-89(158)110(180)150-80(93(122)163)51-66-57-137-70-27-10-9-26-69(66)70,3-2(4,5)1(6)7/h6-10,24-27,57-59,61-64,71-89,137,182H,11-23,28-56,60,116-120H2,1-5H3,(H2,121,159)(H2,122,163)(H,131,138)(H,132,139)(H,140,160)(H,141,165)(H,142,167)(H,143,168)(H,144,164)(H,145,178)(H,146,173)(H,147,174)(H,148,175)(H,149,166)(H,150,180)(H,151,170)(H,152,169)(H,153,176)(H,154,179)(H,155,171)(H,156,172)(H,157,177)(H,161,162)(H4,123,124,133)(H4,125,126,134)(H4,127,128,135)(H4,129,130,136),(H,6,7)/t71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,/m0./s1. InChi Key: JXGHYOXWOPNQOO-KZROFVJCSA-N

Keywords:	(4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37S,40S,43S)-1-amino-31-(2-amino-2-oxoethyl)-43-(((S)-1-(((S)-1-(((R)-4-((S)-1-(((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)pyrrolidin-2-yl)-1-mercapto-3,4-dioxobutan-2-yl)amino)-3-(1H-imidazol-5-yl)-1-
Supplier:	Cayman Chemical
Supplier-Nr:	45287