C5aR2 agonist P32

Description: C5aR2 agonist P32 (Ac-RHYPYWR-OH) is a selective agonist for C5aR2. It has demonstrated the ability to trigger various immunomodulatory activities both in vitro and in vivo, as it can downregulate C5aR1-mediated cellular signaling and can also operate in a C5aR1-independent manner. Smiles: C([C@H](NC([C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H]2N(C([C@H](CC3=CC=C(O)C=C3)NC([C@H](CC4=CN=CN4)NC([C@H](CCCNC(=N)N)NC(C)=O)=O)=O)=O)CCC2)=O)C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)C=5C=6C(NC5)=CC=CC6