[Asn23] beta-Amyloid (1-40), Iowa mutation

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T83507-5mg	5 mg				7 - 10 business days*		-
TGM-T83507-50mg	50 mg				7 - 10 business days*		-

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Description: [Asn23] beta-Amyloid (1-40), Iowa mutation, is a biologically active peptide linked... more

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Product information "[Asn23] beta-Amyloid (1-40), Iowa mutation"

Description: [Asn23] beta-Amyloid (1-40), Iowa mutation, is a biologically active peptide linked to autosomal dominant Alzheimer's Disease in multiple families. This involves the substitution of Asp 23 with Asn, causing severe cerebral amyloid beta-protein angiopathy (CAA). Individuals with this mutation exhibit a missense alteration in the APP gene at position 694, resulting in the mutated beta-amyloid peptide aggregating more quickly and forming toxic fibrils.