AQP4 (201-220)

Description: AQP4 (201-220) is the encephalitogenic epitope of AQP-4. AQP4 (201-220) can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal lesions, and lesions at the gray matter/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica. Target: Aquaporin. Smiles: C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@H](CC3=CN=CN3)N)=O)CC(C)C)=O)=O)C)=O)[C@H](CC)C)=O)CC(N)=O)=O)=O)[C@@H](C)O)=O)=O)C)=O)CO)=O)CCSC)=O)CC(N)=O)(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=CC=C5)C(NCC(=O)N6[C@H](C(O)=O)CCC6)=O)=O)CO)=O)CCCNC(=N)N)=O)C)=O)CCC4