alpha-MSH

Description: alpha-MSH (MSH, amide) is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase. Target: Adenylyl cyclase, Melanocortin Receptor. Smiles: CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O. References: Jo H, et al. Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of alpha-MSH-stimulated melanogenesis. Bioorg Med Chem Lett. 2017 Aug 1,27(15):3374-3377.