alpha-Conotoxin Vc1.1 TFA

Description: alpha-Conotoxin Vc1.1 TFA is a peptide isolated from Conus victoriae and a selective nAChR antagonist that inhibits alpha3alpha5beta2, alpha3beta2 and alpha3beta4, reversing mechanical allodynia in neuropathic pain models and can be used to study neuropathic chronic pain. alpha-Conotoxin Vc1.1 TFA inhibits human dorsal root ganglion nerve excitability and mouse colon nociception via GABA(B) receptors. Target: AChR. Smiles: [H]NCC(N[C@@H](CS)C(N[C@@H](CS)C(N[C@H](C(N[C@@H](CC(O)=O)C(N1CCC[C@H]1C(N[C@H](C(N[C@@H](CS)C(N[C@H](C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC3=CN=CN3)C(N4CCC[C@H]4C(N[C@H](C(N[C@]([H])(C(N[C@@H](CS)C(N)=O)=O)[C@@H](C)CC)=O)CCC(O)=O)=O)=O)=O)=O)=O)CC(N)=O)=O)=O)CCCNC(N)=N)=O)=O)=O)CO)=O)=O)=O.O=C(O)C(F)(F)F