ACTH (4-9) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

Adrenocorticotropic hormone (ACTH) (4-9) is a peptide fragment of ACTH, a peptide hormone produced by the anterior pituitary gland that is involved in the biological stress response. The amino acid sequence of ACTH (4-9) is common to ACTH and alpha- and beta-melanocyte stimulating hormones. ACTH (4-9) (50 µg/kg) reduces neuronal damage induced by dexamethasone (Cay-11015) in mouse hippocampal pyramidal neurons. InChI: InChI=1S/C42H56N12O9S.C2HF3O2/c1-64-17-15-28(43)36(57)50-31(13-14-35(55)56)38(59)53-33(20-26-22-46-23-49-26)40(61)52-32(18-24-8-3-2-4-9-24)39(60)51-30(12-7-16-47-42(44)45)37(58)54-34(41(62)63)19-25-21-48-29-11-6-5-10-27(25)29,3-2(4,5)1(6)7/h2-6,8-11,21-23,28,30-34,48H,7,12-20,43H2,1H3,(H,46,49)(H,50,57)(H,51,60)(H,52,61)(H,53,59)(H,54,58)(H,55,56)(H,62,63)(H4,44,45,47),(H,6,7)/t28-,30-,31-,32-,33-,34-,/m0./s1, InChIKey: LINOGYJLAVAUKT-ZNRQHCRPSA-N, SMILES: [H]N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(O)=O)CC1=CNC2=C1C=CC=C2)=O)=O)CC3=CC=CC=C3)=O)CC4=CN=CN4)=O)=O)CCSC.O=C(O)C(F)(F)F