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ERalpha17p
Item number: TGM-TP2682-10mg
Description: ERalpha17p (ERalpha 295-311), the epitope of the CaM binding site located on estrogen receptor alpha (ER), interacts with calmodulin (CaM) in a calcium-dependent fashion. This peptide is involved in regulating the migration of various cancer cell lines including MCF-7, SK-BR-3, T47D, and MDA-MB-231 via...
| Keywords: | ERalpha (295-311) |
| MW: | 1900.33 D |
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BMAP 28 (bovine)
Item number: TGM-TP2686-10mg
Description: BMAP 28, bovine, is an antimicrobial peptide. It demonstrates antibacterial activity against both Gram-positive and Gram-negative bacteria by increasing cell membrane permeability and causing leakage of cell contents. Furthermore, BMAP 28, bovine, exhibits cytotoxic effects on cancer cells and activated...
| MW: | 3131.85 D |
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d-(KLAKLAK)2, Proapoptotic Peptide
Item number: TGM-TP2687-10mg
Description: d-(KLAKLAK)2 is an antimicrobial and antitumor peptide, notable within the group of antimicrobial peptides, and exhibits strong anticancer properties. It kills bacteria by disrupting their cell membranes, causing leakage of cell contents. Additionally, d-(KLAKLAK)2 inhibits tumor cell proliferation by...
| MW: | 1523.01 D |
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EPI-X4
Item number: TGM-TP2690-10mg
Description: EPI-X4 (hSA408â?"423 peptide), with an IC50 of 8.6 µM, serves as an antagonist for the C-X-C motif chemokine receptor 4 (CXCR4). It inhibits CXCL12-mediated signaling and reduces chemokine-driven migration and invasion of leukemia cells. Furthermore, it demonstrates anti-inflammatory effects in a mouse...
| Keywords: | hSA(408âEUR"423) peptide |
| MW: | 1830.18 D |
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Candidalysin
Item number: TGM-TP2693-10mg
Description: Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix...
| MW: | 3310.11 D |
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YHIEPV
Item number: TGM-TP2694-10mg
Description: YHIEPV (rALP-2, Rubisco anxiolytic-like peptide 2) is a potent, orally active peptide demonstrating anxiolytic properties. Additionally, it enhances leptin sensitivity, contributing to its anti-obesity effects. Smiles:...
| Keywords: | rALP-2, Rubisco anxiolytic-like peptide 2 |
| MW: | 756.85 D |
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A20FMDV2
Item number: TGM-TP2698-10mg
Description: A20FMDV2 is a highly selective alphavbeta6 integrin inhibitor with an IC 50 of 3 nM, demonstrating 1,000-fold greater selectivity for alphavbeta6 compared to other RGD-directed integrins like alphavbeta3, alphavbeta5, and alpha5beta1. This compound can be derived from the foot-and-mouth disease virus...
| MW: | 2163.48 D |
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BING
Item number: TGM-TP2706-10mg
Description: BING is an antimicrobial peptide isolated from Japanese medaka fish. It exhibits broad-spectrum toxicity against pathogenic bacteria, including resistant strains. BING disrupts the periplasmic peptidyl-prolyl isomerase in Gram-negative bacteria and reduces RNA levels of cpxR, which plays a crucial role...
| MW: | 1464.84 D |
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aStAx-35R
Item number: TGM-TP2710-10mg
Description: aStAx-35R is a stapled peptide that antagonizes the nuclear form of beta-catenin, thereby inhibiting Wnt signaling. It competitively inhibits the binding of beta-catenin to TCF4. Additionally, aStAx-35R selectively induces growth inhibition in Wnt-dependent cancer cells. Target: Wnt/beta-catenin....
| MW: | 2392.86 D |
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KK14(R)
Item number: TGM-TP2712-10mg
Description: KK14(R) is a variant of the synthetic peptide KK14, demonstrating antifungal properties against Fusarium culmorum, Penicillium expansum, and Aspergillus niger, with minimum inhibitory concentrations (MICs) of 6.25, 12.5, and 12.5 µg/mL, respectively. KK14(R) also maintains stability under heat and...
| MW: | 1880.29 D |
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cyclo(CLLFVY)
Item number: TGM-TP2717-10mg
Description: Cyclo(CLLFVY) is an inhibitor of hypoxia-inducible factor-1 (HIF-1), exhibiting half-maximal inhibitory concentrations (IC50) of 19 µM in U2OS cells and 16 µM in MCF-7 cells. It binds to the PAS-B domain of HIF-1alpha, inhibiting the dimerization and transcriptional activity of HIF-1. Moreover,...
| MW: | 738.94 D |
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Pardaxin P 4
Item number: TGM-TP2718-10mg
Description: Pardaxin P 4 is an antimicrobial peptide found in the secretions of the Red Sea Moses sole (Red Sea Moses sole). It functions as a biolfilm perforating agent, interacting with phospholipid bilayers of varying compositions to induce cytotoxicity and pore formation. Pardaxin P 4 is used in the research of...
| MW: | 3323.83 D |
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