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PIC1 PA
Item number: TGM-TP3013-10mg
Description: PIC1 PA, a peptide consisting of 15 amino acids, serves as an effective analog of PIC1 that inhibits complement activation mediated by the classical pathway. Functionally, PIC1 PA interferes with the interaction between the C1s-C1r-C1r-C1s/MASPs and the collagen-like region (CLR) of C1q/MBL. It...
| MW: | 1642.98 D |
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PGD97
Item number: TGM-TP3018-10mg
Description: PGD97 is a selective cyclic peptide inhibitor targeting the CAL/CFTR interaction, with its desulfurization-cyclized form exhibiting a KD value of 6 nM for the CAL PDZ domain. It shows a selectivity of at least 130-fold over the NHERF1/2 PDZ domains. PGD97 stabilizes F508del-CFTR on the cell membrane,...
| MW: | 1643.01 D |
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GPLGLAGGWGERDGS
Item number: TGM-TP3038-10mg
Description: GPLGLAGGWG ERDGS is a polypeptide with MMP enzyme responsiveness and tumor-targeting properties, suitable for research on enzyme-guided nanoparticle assembly within tumors. Target: MMP. Smiles:...
| MW: | 1428.51 D |
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ED11
Item number: TGM-TP3043-10mg
Description: ED11 is a potent and selective caspase-6 inhibitor with an IC50 of 12.12 nM. It competes with Htt for the caspase-6 active site, thereby reducing Htt cleavage. ED11 is capable of crossing the blood-brain barrier (BBB) and holds potential for researching Huntington's disease (HD). Target: Caspase....
| MW: | 2850.16 D |
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LH2 peptide
Item number: TGM-TP3047-10mg
Description: LH2 peptide is a pH-responsive, cell-penetrating peptide dimer with the amino acid sequence LHHLCHLLHH LCHLAG. It increases uptake in tumor cells in slightly acidic environments (such as the tumor microenvironment) through histidine residue protonation (pKa approximately 6). When conjugated with the...
| MW: | 1854.21 D |
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NYAD-13
Item number: TGM-TP3048-10mg
Description: NYAD-13 exhibits antiviral activity against the HIV-1IIIB virus, however, it also shows significant cytotoxicity. Target: HIV Protease. Smiles:...
| MW: | 1738.12 D |
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HER2-targeted peptide H6F
Item number: TGM-TP3055-10mg
Description: HER2-targeted peptide H6F is a molecule designed to bind to HER2 and target breast cancer cells, characterized by the amino acid sequence YLFFVFER. It can conjugate with the bifunctional chelator hydrazinonicotinamide (HYNIC) for binding with 99mTc for radiolabeling purposes. Single-photon emission...
| MW: | 1120.3 D |
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IDR-HH2
Item number: TGM-TP3064-10mg
Description: IDR-HH2 is an immunoregulatory peptide with the ability to modulate the host cytokine/chemokine environment. It enhances the adhesion of monocytes and THP-1 cells to fibronectin. Additionally, IDR-HH2 exhibits antibacterial activity, inhibiting P. aeruginosa and S. aureus with MIC values of 75 µg/mL and...
| MW: | 1392.74 D |
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DOTA-Octreotide TFA
Item number: TGM-TP3068-1mg
Description: DOTA-Octreotide TFA consists of the chelating agent DOTA and Octreotide. It is utilized in cancer research through its ability to bind with radioactive elements and is also employed in the synthesis and study of radiolabeled conjugate drugs (RDC). Smiles:...
| MW: | 1519.66 D |
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Vaccarin C
Item number: TGM-TP3069-10mg
Description: Vaccarin C (Compound VIII) is a cyclic heptapeptide with significant antifungal activity, demonstrating a MIC of 6 µg/mL against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes. It also exhibits high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich ascites carcinoma...
| MW: | 812.953 D |
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Dihydrochlamydocin analog-1
Item number: TGM-TP3076-10mg
Description: Dihydrochlamydocinanalog-1 (compound 2) is a Chlamydocin analog that inhibits the deacetylation of histone H4 peptides, with an IC50 of 30 nM. Target: HDAC. Smiles: O=C1N2[C@@](C(=O)N[C@@H](CCCCCC([C@@H](C)O)=O)C(=O)NC(C)(C)C(=O)N[C@H]1CC3=CC=CC=C3)(CCC2)[H]
| MW: | 528.64 D |
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cTEV6-2
Item number: TGM-TP3087-10mg
Description: cTEV6-2 covalently inhibits the Tobacco Etch Virus protease (TEV protease) by binding to its cysteine residue (C151), with an IC50 of 81.7 nM. Target: Virus Protease. Smiles:...
| MW: | 1536.71 D |
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