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ANNULATIN
Item number: TGM-TP2948-10mg
Description: Annulatin, a linear alpha-helical peptide, demonstrates histamine-releasing activity from mast cells and exhibits low hemolytic activity. However, it does not show antimicrobial activities against any of the tested microbes. Smiles: O=C1C(OC)=C(OC=2C=C(O)C=C(O)C12)C=3C=C(O)C(O)=C(O)C3
| MW: | 332.26 D |
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S1b3inL1
Item number: TGM-TP2956-10mg
Description: S1b3inL1 is a macrocylcic peptide inhibitor of the SARS-CoV-2 spike protein. It binds with high affinity to a conserved site on the spike protein, effectively suppressing the infection of various SARS-CoV-2 variants. S1b3inL1 exhibits antiviral activity. Target: SARS-CoV. Smiles:...
| MW: | 2232.61 D |
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Tkip
Item number: TGM-TP2958-10mg
Description: Tkip is a specific inhibitor of JAK2. It binds to the autophosphorylation site of JAK2, thereby inhibiting JAK2 autophosphorylation and the phosphorylation of the IFN-gamma receptor subunit IFNGR-1. Tkip can suppress the antiviral activity of IFN-gamma and the expression of MHC class I molecules. Tkip...
| MW: | 1684.03 D |
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Capsid assembly inhibitor
Item number: TGM-TP2961-10mg
Description: Capsid assembly inhibitor is a 12-mer peptide that binds to the Gag capsid (CA) domain, effectively inhibiting the assembly of both immature and mature-like HIV-1 capsid particles in vitro. Target: Others. Smiles:...
| MW: | 1445.57 D |
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PKHB1
Item number: TGM-TP2999-10mg
Description: PKHB1 is a thrombospondin-1 peptide mimetic known for its antitumor properties. It induces mitochondrial alterations, ROS generation, intracellular Ca+ accumulation, and calcium-dependent cell death in breast cancer cells. Additionally, PKHB1 promotes immune system activation through immunogenic cell...
| MW: | 1384.73 D |
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NBD peptide
Item number: TGM-TP3009-10mg
Description: NBD peptide inhibits the NF-kappaB signaling pathway by preventing the binding of the NEMO-IKK complex. It exhibits anti-inflammatory activity by blocking the production of pro-inflammatory cytokines. Additionally, NBD peptide demonstrates immunosuppressive effects through the regulation of immune...
| MW: | 1349.44 D |
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RI-OR2-TAT
Item number: TGM-TP3015-10mg
Description: RI-OR2-TAT is a brain-penetrable inhibitor targeting beta-amyloid (beta-Amyloid) oligomerization. It is engineered by integrating the HIV protein transduction domain TAT into RI-OR2. RI-OR2-TAT binds to Abeta42 fibrils with a Kd value of 58-125 nM. It reduces Abeta aggregation and plaque levels,...
| MW: | 2662.16 D |
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![ANP [Des18-22] 4-23 amide rat](https://www.biomol.com/media/image/1a/g0/2f/TGM-TP3030-10mg_200x200.png "ANP [Des18-22] 4-23 amide rat")
ANP [Des18-22] 4-23 amide rat
Item number: TGM-TP3030-10mg
Description: ANP [Des18-22] 4-23 amide rat is a peptide fragment of rat atrial natriuretic peptide (ANP) that specifically binds to NPR-C. Target: Natriuretic peptide. Smiles:...
| MW: | 1594.82 D |
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P160 peptide
Item number: TGM-TP3031-10mg
Description: P160 peptide is a breast cancer-targeting peptide that binds to the keratin 1 (KRT1) receptor in breast cancer cells, with a Kd of approximately 1.1 µM. It shows significant potential for targeted drug delivery to breast cancer cells. P160 peptide enhances the cellular uptake and anticancer activity of...
| MW: | 1536.79 D |
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Tyr3-Octreotate acetate
Item number: TGM-TP3036-10mg
Description: Tyr3-Octreotate acetate is a somatostatin analogue with a high tumor uptake rate that can be labeled with radioactive metals, thus exhibiting antitumor activity. It is utilized in the synthesis and study of radiolabeled conjugate drugs (RDC). Smiles:...
| MW: | 1169.33 D |
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CNI103
Item number: TGM-TP3040-10mg
Description: CNI103 is a potent and metabolically stable inhibitor of the cell-permeable peptide, calcineurin. It selectively inhibits the interaction between calcineurin and NFATc3 (KD=16 nM), thereby preventing the activation of NFATc3 both in vitro and in vivo. CNI103 is applicable for research in acute...
| MW: | 2565.8 D |
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Poneratoxin acetate
Item number: TGM-TP3045-1mg
Description: Poneratoxin acetate is a neurotoxic peptide and modulator of NaV1.6/NaV1.7, lowering the activation threshold of voltage-gated sodium channels and causing pain. Target: Sodium Channel. Smiles:...
| MW: | 2756.35 D |
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