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N'-Nitro-D-arginine
Item number: TGM-T9537-500mg
Description: N'-Nitro-D-arginine (N'-Nitro-D-arginine) is a Building Block. Target: NO Synthase, Others. Smiles: N[C@H](CCCNC(=N)N[N+]([O-])=O)C(O)=O. References: Pudupakkam S, Harris KA, Jamieson WG, DeRose G, Scott JA, Carson MW, Schlag MG, Kvietys PR, Potter RF. Ischemic tolerance in skeletal muscle: role of...
| Keywords: | N'-Nitro-D-arginine , H-D-Arg(NO2)-OH , (R)-2-Amino-5-(3-nitroguanidino)pentanoic acid |
| MW: | 2192 D |
290.00€
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Icotrokinra
Item number: TGM-T89073-10mg
Description: Icotrokinra is an orally bioavailable and highly selective antagonist of the interleukin-23 receptor (IL-23R), thereby interfering with IL-23-mediated signaling cascades. Icotrokinra inhibits IL-23-induced STAT3 phosphorylation in peripheral blood mononuclear cells with an IC50 value of 5.6 pM, and it...
| Keywords: | JNJ2113 , JNJ-2113 , JNJ-77242113 , PN-235 , JNJ77242113 , PN235 |
| MW: | 189817 D |
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Substance P acetate
Item number: TGM-TP1087L-100mg
Description: Substance P acetate is a peptide mainly secreted by neurons and is involved in many biological processes including nociception and inflammation. Substance P acetate is a neuroinflammatory factor that can act as a neurotransmitter and neuromodulator in the central nervous system and can be used to study...
| Keywords: | Substance P acetate (33507-63-0 Free base) , Neurokinin P acetate |
| MW: | 1407.68 D |
From 46.00€
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N-Acetylcarnosine
Item number: TGM-TP1088-1g
Description: N-Acetylcarnosine (N-Acetyl-L-carnosine) is thought to be able to combat some of the effects of oxidative stress as it has anti-oxidant properties. Target: Others. Smiles: CC(=O)NCCC(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O. References: Babizhayev MA, et al. N-Acetylcarnosine, a natural histidine-containing...
| Keywords: | N-Acetyl-L-carnosine |
| MW: | 268.27 D |
36.00€
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Fmoc-N-Me-Ala-OH
Item number: TGM-TP1437-1mL
Description: Fmoc-N-Me-Ala-OH is available for the peptide-coupling reaction. Target: Others, Amino Acids and Derivatives. Smiles: C[C@H](N(C)C(=O)OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)C(O)=O. References: Harris KS, et al. Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl...
| MW: | 325.36 D |
29.00€
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![[Gln144]-PLP (139-151)](https://www.biomol.com/media/image/04/0c/c5/TGM-TP2659-10mg_200x200.png "[Gln144]-PLP (139-151)")
[Gln144]-PLP (139-151)
Item number: TGM-TP2659-10mg
Description: [Gln144]-PLP(139-151) is an experimental antigen employed to investigate the cross-reactivity of T cells to self and non-self antigens. It activates T cells by binding to the T-cell Receptor (TCR), initiating an immune response. It is useful in the study of autoimmune disease regulation. Smiles:...
| Keywords: | Q144-PLP(139-151) |
| MW: | 1463.64 D |
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HBP08
Item number: TGM-TP2661-10mg
Description: HBP08 is a selective inhibitor that disrupts the interaction between CXCL12 and HMGB1. It demonstrates a high affinity for HMGB1 with a dissociation constant (K d) of 0.8 µM and effectively inhibits cell migration induced by CXCL12. Smiles:...
| MW: | 1260.36 D |
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p53 (232-240)
Item number: TGM-TP2662-10mg
Description: p53 (232-240), a peptide derived from the 232-240 amino acid sequence of the human tumor suppressor protein p53, improves its binding affinity to the Major Histocompatibility Complex (MHC). This enhancement increases the immunogenicity of the peptide, boosting the immune system's response to tumor...
| MW: | 1066.3 D |
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WEYIPNV
Item number: TGM-TP2668-10mg
Description: WEYIPNV is a ligand of SurA, specifically binding to the P1 domain of SurA (Kd: 1-14 µM). Its binding facilitates the release of the P1 domain from the core domain. Smiles:...
| MW: | 920.02 D |
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KGYY15
Item number: TGM-TP2671-10mg
Description: KGYY15 (Mouse KGYY15), a peptide that targets CD40, exhibits weak inhibition of the CD40-CD40L interaction, with an IC50 exceeding 1 mM. At a concentration of 100 µM, KGYY15 activates the NF-kappaB pathway by 33%. Target: TNF. Smiles:...
| Keywords: | KGYY15 peptide , Mouse KGYY15 |
| MW: | 1817.12 D |
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His-Cys-Lys-Phe-Trp-Trp
Item number: TGM-TP2672-10mg
Description: His-Cys-Lys-Phe-Trp-Trp functions as an inhibitor of the human immunodeficiency virus (HIV) integrase, exhibiting an IC50 value of 2 µM. Target: HIV Protease. Smiles:...
| MW: | 906.06 D |
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HIV gp120 (318-327)
Item number: TGM-TP2676-10mg
Description: HIVgp120 (318-327) is a short sequence (rgpgrafvti) from the envelope peptide of the HIV-1 IIIB strain, corresponding to the conserved C-terminal region of the glycoprotein. It is part of the HIV vaccine V3 peptide epitope, also known as the I10 peptide. However, HIVgp120 (318-327) lacks the A2 anchor...
| MW: | 1073.25 D |
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