Blocking Peptides

Peptide corresponding to amino acids 13 to 28 of human GPR15 (1). The sequence differs from those of African green monkey and pig-tailed macaque BOB by one amino acid (2), Human immunodeficiency virus (HIV) and related viruses require coreceptors to infect target cells. Some G protein-coupled receptors including...

Peptide is used to block HER2/ErbB2 Rabbit mAb reactivity in immunohistochemistry protocols. The ErbB2 (HER2) proto-oncogene encodes a transmembrane receptor-like glycoprotein of 185kD with intrinsic tyrosine kinase activity (1). ErbB2 does not have any known ligand. However, the kinase activity of ErbB2 can be...

Peptide is used to block HP1alpha Antibody and HP1alpha (C7F11) Rabbit mAb reactivity in immunohistochemistry protocols. Heterochromatin protein 1 (HP1) is a family of heterochromatic adaptor molecules involved in both gene silencing and higher order chromatin structure (1). All three HP1 family members (alpha, beta...

Peptide is used to block Acetyl-Histone H3 (Lys9) Rabbit mAb and Acetyl-Histone H3 (Lys9) Antibody reactivity in immunohistochemistry protocols. Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B,...

Peptide is used to block H5110-14J3 Di-Methyl Histone H3 (Lys4) Rabbit mAb reactivity in immunohistochemistry protocols. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging,...

Peptide is used to block Tri-MethylHistone H3 (Lys4) Rabbit mAb and Tri-Methyl-Histone H3 (Lys4) Antibody reactivity in immunohistochemistry protocols. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. Originally thought to function as a static...

Synthetic peptide (TGYEARLITFGT) corresponding to amino acids 2 to 13 of human ILP-2 (1). Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins....

Peptide corresponding to amino acids 2 to 21 of mouse ICAD (2). , , Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death...

Peptide corresponding to amino acids 312 to 331 of mouse ICAD (2). , Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death...

Peptide corresponding to amino acids 699 to 715 of human IKKa (1,2), which differs from corresponding murine sequence by one amino acid. , , Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB...

Peptide corresponding to amino acids 658 to 674 of human IKKa (1,2), which differs from corresponding murine sequence by one amino acid. , , Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB...

Peptide corresponding to amino acids 662 to 680 of human IKKb (3,4), which differs from corresponding murine sequence by one amino acid (5). , , Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses....