Blocking Peptides

Peptide corresponding to amino acids 200 to 217 of human CIDE-A (5). , Apoptosis is related to many diseases and induced by a family of cell death receptors. Cell death signals are transduced by DD-, DED-, or CARD-containing molecules and members of the caspase family of proteases. These death signals finally cause...

Peptide corresponding to amino acids 204 to 219 of murine CIDE-B (1). , Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death...

Peptide corresponding to amino acids 200 to 214 of mouse CIDE-A (1). , Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death...

Peptide is used to block Cleaved Caspase-8 (Asp391) Rabbit mAb reactivity in immunohistochemistry protocols. Apoptosis induced through CD95 receptor (Fas/APO-1) and tumor necrosis factor receptor 1 (TNFR1) activates caspase-8 and leads to the release of the caspase8 active fragments, p18 and p10 (1-3). Activated...

Peptide corresponding to amino acids 175 to 189 of human CX3CR1 (1,2). , CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively, (1-4). The encoded seven...

Peptide corresponding to aa2-21 of human CX3CR1 (1). The sequence differs from those of mouse and rat CX3CR1 by four amino acids (3,4). CX3CR1 is one of the chemokine receptors that is required as a coreceptor for HIV infection. The genes encoding human, murine, and rat CX3CR1 were cloned and designated V28 and...

Control Peptide for C8350, AA 82-196 in the second extracellular loop (EL) of human CXCR4. Human immunodeficiency virus (HIV) and related viruses require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor...

Control Peptide for C8375, AA1-14 in the N-Terminus (NT) of human CXCR4. Human immunodeficiency virus (HIV) and related viruses require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new...

Peptide (ARRKALHPRRRSSTS) corresponding to amino acids 356 to 370 of human DAPK2 (1,2). The sequence of this antigenic peptide is identical to the corresponding amino acids of mouse origin (1,2), Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain...

Peptide is used to block DARPP-32 Rabbit mAb reactivity in immunohistochemistry protocols. DARPP-32 (dopamine and cyclic AMPregulated phosphoprotein, relative molecular mass 32,000) is a cytosolic protein highly enriched in medium-sized spiny neurons of the neostriatum (1). It is a bifunctional signaling molecule...

Peptide corresponding to amino acids 722 to 740 at C-terminus of human Daxx 1,2. Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death...

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL (1-3)....