Blocking Peptides

Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf-1, ARC, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified in human...

Peptide (linear) corresponding to amino acids 1356-1375 of human ASK1 (1). This sequence is different from that of mouse by last two amino acids (3). Mitogen-activated protein (MAP) kinase cascades are activated in response to various extracellular stimuli, including cytokines, growth factors and environmental...

Peptide corresponding to amino acids 485 to 501 of human BACE (1)., Accumulation of the amyloid-b (Ab) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. Ab peptide is generated by proteolytic cleavage of the b-amyloid protein precursor (APP) at b-and g-sites by two...

Peptide corresponding to amino acids 496 to 511 of human BACE2 (4). Accumulation of the amyloid-b (Ab) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. Ab peptide is generated by proteolytic cleavage of the b-amyloid protein precursor (APP) at b-and g-sites by proteases....

Peptide (APTPGPGTPAERHADG) corresponding to amino acids 44 to 59 of human BACE2 (4). Accumulation of the amyloid-b (Ab) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. Ab peptide is generated by proteolytic cleavage of the b-amyloid protein precursor (APP) at b-and...

Synthetic peptide (ALNGEENRNGAGPR) corresponding to amino acids 171 to 184 of human Bmf (1). Apoptosis is related to many diseases and development. Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain....

Synthetic peptide (EPSQCVEELEDDV) corresponding to amino acids 2 to 14 of human Bmf (1). This sequence differs from that of mouse by one amino acid. Apoptosis is related to many diseases and development. Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death....

Peptide corresponding to amino acids 5 to 19 of human origin (1-6). Apoptosis is related to many diseases including cancer. Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators...

Peptide corresponding to amino acids 22 to 40 of human origin (1). The sequence is identical to that of mouse and differs from that of rat by one amino acid., , Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent...

Peptide is used to block BiP Rabbit mAb reactivity in immunohistochemistry and western blot protocols. Secretory and transmembrane proteins are synthesized on polysomes and translocated into the endoplasmic reticulum (ER). Inside the ER, these proteins are often modified by disulfide bond formation, amino-linked...

Peptide corresponding to amino acids 77 to 92 of human origin, which are identical to those of mouse Bnip3L (3). See cat# B2200 for corresponding antibody., , Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death...

Peptide corresponding to amino acids 11 to 25 of human Bonzo/STRL33 (1,2)., Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor...