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PKHB1
Item number: TGM-TP2999-10mg
Description: PKHB1 is a thrombospondin-1 peptide mimetic known for its antitumor properties. It induces mitochondrial alterations, ROS generation, intracellular Ca+ accumulation, and calcium-dependent cell death in breast cancer cells. Additionally, PKHB1 promotes immune system activation through immunogenic cell...
| MW: | 1384.73 D |
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NBD peptide
Item number: TGM-TP3009-10mg
Description: NBD peptide inhibits the NF-kappaB signaling pathway by preventing the binding of the NEMO-IKK complex. It exhibits anti-inflammatory activity by blocking the production of pro-inflammatory cytokines. Additionally, NBD peptide demonstrates immunosuppressive effects through the regulation of immune...
| MW: | 1349.44 D |
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RI-OR2-TAT
Item number: TGM-TP3015-10mg
Description: RI-OR2-TAT is a brain-penetrable inhibitor targeting beta-amyloid (beta-Amyloid) oligomerization. It is engineered by integrating the HIV protein transduction domain TAT into RI-OR2. RI-OR2-TAT binds to Abeta42 fibrils with a Kd value of 58-125 nM. It reduces Abeta aggregation and plaque levels,...
| MW: | 2662.16 D |
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![ANP [Des18-22] 4-23 amide rat](https://www.biomol.com/media/image/1a/g0/2f/TGM-TP3030-10mg_200x200.png "ANP [Des18-22] 4-23 amide rat")
ANP [Des18-22] 4-23 amide rat
Item number: TGM-TP3030-10mg
Description: ANP [Des18-22] 4-23 amide rat is a peptide fragment of rat atrial natriuretic peptide (ANP) that specifically binds to NPR-C. Target: Natriuretic peptide. Smiles:...
| MW: | 1594.82 D |
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P160 peptide
Item number: TGM-TP3031-10mg
Description: P160 peptide is a breast cancer-targeting peptide that binds to the keratin 1 (KRT1) receptor in breast cancer cells, with a Kd of approximately 1.1 µM. It shows significant potential for targeted drug delivery to breast cancer cells. P160 peptide enhances the cellular uptake and anticancer activity of...
| MW: | 1536.79 D |
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Tyr3-Octreotate acetate
Item number: TGM-TP3036-10mg
Description: Tyr3-Octreotate acetate is a somatostatin analogue with a high tumor uptake rate that can be labeled with radioactive metals, thus exhibiting antitumor activity. It is utilized in the synthesis and study of radiolabeled conjugate drugs (RDC). Smiles:...
| MW: | 1169.33 D |
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CNI103
Item number: TGM-TP3040-10mg
Description: CNI103 is a potent and metabolically stable inhibitor of the cell-permeable peptide, calcineurin. It selectively inhibits the interaction between calcineurin and NFATc3 (KD=16 nM), thereby preventing the activation of NFATc3 both in vitro and in vivo. CNI103 is applicable for research in acute...
| MW: | 2565.8 D |
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Poneratoxin acetate
Item number: TGM-TP3045-1mg
Description: Poneratoxin acetate is a neurotoxic peptide and modulator of NaV1.6/NaV1.7, lowering the activation threshold of voltage-gated sodium channels and causing pain. Target: Sodium Channel. Smiles:...
| MW: | 2756.35 D |
47.00€
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Cyclic(YCDGFYACYMDV)
Item number: TGM-TP3053-10mg
Description: Cyclic(YCDGFYACYM DV) is a HER2 signaling pathway inhibitor with anticancer properties. In aqueous solution, Cyclic(YCDGFYACYMDV) self-assembles into nanoparticles that target HER2 on cancer cells, converting into nanofibrils. This process disrupts HER2 dimerization and subsequent downstream signaling,...
| MW: | 1447.61 D |
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Ac-MRGDH-NH2
Item number: TGM-TP3057-10mg
Description: Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Lambda- and Delta-[Ru(Ph2phen)2(kappaS,kappaN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua...
| MW: | 655.727 D |
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RSRGVFF
Item number: TGM-TP3062-10mg
Description: RSRGVFF (FOXP3 inhibitor P60) is a mixed angiotensin-converting enzyme (ACE) inhibitor with the ability to penetrate the blood-brain barrier, exhibiting an IC50 value of 5.01 µM. It binds to both active and inactive sites of ACE and its substrate HHL complex, thereby reducing the catalytic activity of...
| MW: | 867.994 D |
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RES-701-1
Item number: TGM-TP3073-10mg
Description: RES-701-1 is a cyclic peptide consisting of 16 common L-amino acids. It acts as a specific antagonist of the ETB receptor. RES-701-1 inhibits the binding of 125I-ET-1 (125I-labeled endothelin (ET)-1) to the ETB receptor, with an IC50 value of 10 nM. Target: Endothelin Receptor. Smiles:...
| MW: | 2043.16 D |
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