No results were found for the filter!
Taspoglutide acetate
Item number: TGM-TP2906-10mg
Description: Taspoglutide, acting as an agonist for the glucagon-like peptide-1 receptor (GLP-1R, Ki = 1.1 nM for the human receptor), induces cAMP accumulation in CHO-K1 cells expressing human GLP-1R (EC50 = 0.06 nM). In oral glucose tolerance tests conducted on Zucker diabetic fatty rats, Taspoglutide...
| Keywords: | BIM-51077C , [Aib8,35]hGLP-1(7-36)NH2 |
| MW: | 3339.76 D |
Please request pricing for this article.
XIAP Tracer mF-Smac
Item number: TGM-TP2907-10mg
Description: XIAP Tracer mF-Smac, a fluorescently labeled peptide, functions as an acceptor dye in conjunction with a terbium-labeled BIR domain antibody for TR-FRET assays. The binding affinities (Kd values) are measured at 4.7 nM for BIR3 (XIAP) and 17.9 nM in XIAP polarization assays. Smiles:...
| MW: | 989.08 D |
Please request pricing for this article.
Drp1 peptide inhibitor P110
Item number: TGM-TP2908-10mg
Description: Compound P110 (Drp1 peptide inhibitor P110) is a selective Drp1 peptide inhibitor with neuroprotective effects. It inhibits the activation of Drp1, prevents Drp1 mitochondrial translocation induced by MPTP, and alleviates dopamine neuron loss, dopaminergic terminal damage, and behavioral deficits caused...
| MW: | 2411.78 D |
Please request pricing for this article.
WYRGRL
Item number: TGM-TP2912-10mg
Description: WYRGRL is a peptide that targets collagen II alpha1 (collagen II alpha1) through binding interaction. This short chondro-targeting peptide sequence enhances the targeting efficiency of peptide-functionalized nanoplatforms for cartilage in vivo, increasing it by approximately 72 times. Target: MMP....
| MW: | 849.98 D |
Please request pricing for this article.
BMP-4
Item number: TGM-TP2930-10mg
Description: BMP-4, a heparin-binding peptide, exhibits anti-inflammatory and anti-chondrogenic properties. In murine chondrocytes and macrophages, it effectively mitigates inflammation and alleviates symptoms of various arthritides by dose-dependently suppressing the expression of inflammatory proteins such as...
| MW: | 1308.52 D |
Please request pricing for this article.
HB-107
Item number: TGM-TP2932-10mg
Description: HB-107 is a peptide known for its wound healing properties. This compound promotes keratinocyte proliferation and increased leukocyte infiltration at the wound site. Additionally, HB-107 stimulates the secretion of interleukin 8 (IL-8) in cultured endothelial cells. It holds promise for research in...
| MW: | 2331.84 D |
Please request pricing for this article.
T-22
Item number: TGM-TP2933-10mg
Description: T-22 ([Tyr5,12,Lys7]-Polyphemusin II) is a novel anti-HIV synthetic peptide with an EC50 of 0.008 µg/mL and a CC50 of 54 µg/mL. In addition to its antiviral properties, T-22 enhances tomato plant height, photosynthesis, total chlorophyll content, and overall plant gas exchange, and it exhibits...
| Keywords: | [Tyr5,12,Lys7]-Polyphemusin II |
| MW: | 2486.97 D |
Please request pricing for this article.
VU0506013
Item number: TGM-TP2947-10mg
Description: VU0506013 is a high-affinity positive allosteric modulator (PAM) of the neuropeptide Y4 receptor. This compound demonstrates nanomolar-level affinity and notable selectivity in engineered cell lines and the descending colon mucosa of mice that naturally express Y4R. VU0506013 presents a promising...
| Keywords: | SR-01000917304 , AKOS024476467 , SR-01000917304-1 , F2947-0623 , VU0506013-1 |
| MW: | 369.41 D |
Please request pricing for this article.
ANNULATIN
Item number: TGM-TP2948-10mg
Description: Annulatin, a linear alpha-helical peptide, demonstrates histamine-releasing activity from mast cells and exhibits low hemolytic activity. However, it does not show antimicrobial activities against any of the tested microbes. Smiles: O=C1C(OC)=C(OC=2C=C(O)C=C(O)C12)C=3C=C(O)C(O)=C(O)C3
| MW: | 332.26 D |
Please request pricing for this article.
S1b3inL1
Item number: TGM-TP2956-10mg
Description: S1b3inL1 is a macrocylcic peptide inhibitor of the SARS-CoV-2 spike protein. It binds with high affinity to a conserved site on the spike protein, effectively suppressing the infection of various SARS-CoV-2 variants. S1b3inL1 exhibits antiviral activity. Target: SARS-CoV. Smiles:...
| MW: | 2232.61 D |
Please request pricing for this article.
Tkip
Item number: TGM-TP2958-10mg
Description: Tkip is a specific inhibitor of JAK2. It binds to the autophosphorylation site of JAK2, thereby inhibiting JAK2 autophosphorylation and the phosphorylation of the IFN-gamma receptor subunit IFNGR-1. Tkip can suppress the antiviral activity of IFN-gamma and the expression of MHC class I molecules. Tkip...
| MW: | 1684.03 D |
Please request pricing for this article.
Capsid assembly inhibitor
Item number: TGM-TP2961-10mg
Description: Capsid assembly inhibitor is a 12-mer peptide that binds to the Gag capsid (CA) domain, effectively inhibiting the assembly of both immature and mature-like HIV-1 capsid particles in vitro. Target: Others. Smiles:...
| MW: | 1445.57 D |
Please request pricing for this article.