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Sp-Uridine-5'-O-(1-thiotriphosphate) sodium
Item number: TGM-T83823-100mg
Description: Sp-Uridine-5'-O-(1-thiotriphosphate) (Sp-UTP-alpha-S) acts as a nucleotide agonist for purinergic Y2 (P2Y2) and P2Y4 receptors, efficiently inducing inositol phosphate accumulation in 1321N1 astrocytoma cells that express these receptors, with half-maximal effective concentrations (EC50s) of 14 µM and...
| Keywords: | Sp-UTP-alpha-S |
| MW: | 588.14 D |
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LHC165 hydrate
Item number: TGM-T83842-100mg
Description: LHC165, a toll-like receptor 7 (TLR7) agonist, stimulates the immune system's response by activating TLR7. Smiles: NC1=C(N=C2)C(C=C2CCC(C=CC(OCCOCCC(F)(F)[P](O)(O)=O)=C3)=C3C)=C(C=CC(CCC(O)=O)=C4)C4=N1.O
| MW: | 603.55 D |
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Angiotensin II antipeptide
Item number: TGM-T85651-10mg
Description: Angiotensin II antipeptide, a peptide and inverse agonist of the AR1 receptor, is encoded by mRNA complementary to that encoding Angiotensin II itself [1]. Target: RAAS. Smiles:...
| MW: | 899 D |
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LRRKtide TFA
Item number: TGM-T83737-100mg
Description: LRRKtide, a peptide substrate for leucine-rich repeat kinase 2 (LRRK2)â?"an enzyme often mutated in Parkinson's disease patientsâ?"corresponds to amino acids 550-564 of the membrane-organizing extension spike protein (moesin). It serves to identify inhibitors of LRRK2. Smiles:...
| Keywords: | Moesin (550-564) , Membrane-organizing Extension Spike Protein (550-564) |
| MW: | 1931.3 D |
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PTD2 TFA
Item number: TGM-T83850-100mg
Description: PTD2, derived from the histone 4 sequence, acts as a peptide inhibitor against Wolf-Hirschhorn syndrome candidate 1 (WHSC1, IC50 = 22 µM), a histone methyltransferase. Smiles: NC([C@@]([C@H](CC)C)([H])NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](C(C)C)NC(CNC(C)=O)=O)=O)CCCC)=O)=O)=O.OC(C(F)(F)F)=O
| MW: | 597.8 D |
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1-Arachidoyl Lysophosphatidic Acid sodium
Item number: TGM-T83879-100mg
Description: 1-Arachidoyl lysophosphatidic acid (1-arachidoyl LPA), a glycerophospholipid with arachidic acid at the sn-1 position, functions as an agonist for lysophosphatidic acid receptor 1 (LPA1). It effectively induces calcium mobilization in primary human lung fibroblasts at an EC50 value of 3.6 µM, given...
| Keywords: | 1-Arachidoyl LPA , LPA(20:0) , 1-Eicosanoyl-Lysophosphatidic Acid |
| MW: | 488.57 D |
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6-hydroxy Buspirone
Item number: TGM-T83909-100mg
Description: 6-Hydroxy Buspirone, an active metabolite of the anxiolytic compound buspirone, is produced via the cytochrome P450 (CYP) isoform CYP3A4. This compound exhibits affinity for the serotonin (5-HT) receptor subtype 5-HT1A, demonstrating efficacy in the rat hippocampus and dorsal raphe with half-maximal...
| Keywords: | BMY 28674 , BMS-52821 |
| MW: | 401.5 D |
From 1,440.00€
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Elamipretide Triacetate
Item number: TGM-T8644-200mg
Description: Elamipretide Triacetate (Elamipretide TriTFA) is an aromatic-cationic tetrapeptide that readily penetrates cell membranes and transiently localizes to the inner mitochondrial membrane where it associates with cardiolipin.It has been used in trials studying the treatment of Leber's Hereditary Optic...
| Keywords: | Elamipretide TriTFA |
| MW: | 819.94 D |
From 34.00€
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Pexiganan acetate
Item number: TGM-T84862-100mg
Description: Pexiganan acetate (MSI 78) is a synthetic cationic peptide composed of 22 amino acids and demonstrates potent antibacterial activity. Pexiganan acetate is an analogue of magainin 2, which is a naturally occurring host defense peptide originally isolated from frog skin. The antibacterial action of...
| Keywords: | MSI 78 , Cytolex , MSI78 |
| MW: | 2477.22 D |
From 142.00€
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Cathepsin L-IN-4
Item number: TGM-T86008-100mg
Description: Cathepsin L-IN-4 is a cathepsin L inhibitor with IC50 in the nanomolar range [1]. Target: Cysteine Protease. Smiles: S(N[C@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C=O)=O)[C@H](CC)C)(=O)(=O)C=3C4=C(C=CC3)C=CC=C4
| Keywords: | 1-Naphthalenesulfonyl-Ile-Trp-CHO |
| MW: | 491.6 D |
From 1,440.00€
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Fusion Inhibitory Peptide
Item number: TGM-T86480-10mg
Description: Fusion Inhibitory Peptide (Z-D-Phe-Phe-Gly-OH, FIP, Virus Replication Inhibitory Peptide) effectively blocks virus replication by inhibiting the membrane fusion activity of a specific viral glycoprotein [1]. Target: Influenza Virus. Smiles:...
| Keywords: | Z-D-Phe-Phe-Gly-OH , Virus Replication Inhibitory Peptide |
| MW: | 503.55 D |
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LAU-0901
Item number: TGM-T83777-100mg
Description: LAU-0901, a platelet-activating factor (PAF) receptor antagonist, demonstrates efficacy in reducing infarct volume and enhancing neurological function in rats subjected to middle cerebral artery occlusion (MCAO)-induced cerebral ischemia, at doses of 30, 60, and 90 mg/kg. Furthermore, it diminishes...
| MW: | 612.54 D |
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