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EPI-X4
Item number: TGM-TP2690-10mg
Description: EPI-X4 (hSA408â?"423 peptide), with an IC50 of 8.6 µM, serves as an antagonist for the C-X-C motif chemokine receptor 4 (CXCR4). It inhibits CXCL12-mediated signaling and reduces chemokine-driven migration and invasion of leukemia cells. Furthermore, it demonstrates anti-inflammatory effects in a mouse...
| Keywords: | hSA(408âEUR"423) peptide |
| MW: | 1830.18 D |
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Candidalysin
Item number: TGM-TP2693-10mg
Description: Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix...
| MW: | 3310.11 D |
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YHIEPV
Item number: TGM-TP2694-10mg
Description: YHIEPV (rALP-2, Rubisco anxiolytic-like peptide 2) is a potent, orally active peptide demonstrating anxiolytic properties. Additionally, it enhances leptin sensitivity, contributing to its anti-obesity effects. Smiles:...
| Keywords: | rALP-2, Rubisco anxiolytic-like peptide 2 |
| MW: | 756.85 D |
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A20FMDV2
Item number: TGM-TP2698-10mg
Description: A20FMDV2 is a highly selective alphavbeta6 integrin inhibitor with an IC 50 of 3 nM, demonstrating 1,000-fold greater selectivity for alphavbeta6 compared to other RGD-directed integrins like alphavbeta3, alphavbeta5, and alpha5beta1. This compound can be derived from the foot-and-mouth disease virus...
| MW: | 2163.48 D |
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BING
Item number: TGM-TP2706-10mg
Description: BING is an antimicrobial peptide isolated from Japanese medaka fish. It exhibits broad-spectrum toxicity against pathogenic bacteria, including resistant strains. BING disrupts the periplasmic peptidyl-prolyl isomerase in Gram-negative bacteria and reduces RNA levels of cpxR, which plays a crucial role...
| MW: | 1464.84 D |
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aStAx-35R
Item number: TGM-TP2710-10mg
Description: aStAx-35R is a stapled peptide that antagonizes the nuclear form of beta-catenin, thereby inhibiting Wnt signaling. It competitively inhibits the binding of beta-catenin to TCF4. Additionally, aStAx-35R selectively induces growth inhibition in Wnt-dependent cancer cells. Target: Wnt/beta-catenin....
| MW: | 2392.86 D |
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KK14(R)
Item number: TGM-TP2712-10mg
Description: KK14(R) is a variant of the synthetic peptide KK14, demonstrating antifungal properties against Fusarium culmorum, Penicillium expansum, and Aspergillus niger, with minimum inhibitory concentrations (MICs) of 6.25, 12.5, and 12.5 µg/mL, respectively. KK14(R) also maintains stability under heat and...
| MW: | 1880.29 D |
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cyclo(CLLFVY)
Item number: TGM-TP2717-10mg
Description: Cyclo(CLLFVY) is an inhibitor of hypoxia-inducible factor-1 (HIF-1), exhibiting half-maximal inhibitory concentrations (IC50) of 19 µM in U2OS cells and 16 µM in MCF-7 cells. It binds to the PAS-B domain of HIF-1alpha, inhibiting the dimerization and transcriptional activity of HIF-1. Moreover,...
| MW: | 738.94 D |
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Pardaxin P 4
Item number: TGM-TP2718-10mg
Description: Pardaxin P 4 is an antimicrobial peptide found in the secretions of the Red Sea Moses sole (Red Sea Moses sole). It functions as a biolfilm perforating agent, interacting with phospholipid bilayers of varying compositions to induce cytotoxicity and pore formation. Pardaxin P 4 is used in the research of...
| MW: | 3323.83 D |
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GPR110 peptide agonist P12
Item number: TGM-TP2719-10mg
Description: GPR110 peptide agonist P12 is a peptide that acts as an agonist for GPR110. This compound markedly enhances the initial rate of G protein GTPgammaS binding stimulated by GPR110. It mimics the action of the natural ligand, causing the extracellular domain (ECD) of GPR110 to dissociate from the...
| MW: | 1325.57 D |
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Humanized anti-tac (HAT) binding peptide
Item number: TGM-TP2721-10mg
Description: Humanized anti-tac (HAT) binding peptide is a peptide that specifically binds to the Fc region of HAT. HAT is a humanized monoclonal antibody targeting the low-affinity p55 subunit of the interleukin IL-2 receptor. The peptide can be utilized in the development of affinity chromatography media for the...
| MW: | 1350.56 D |
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Sarafotoxin S6d
Item number: TGM-TP2726-10mg
Description: Sarafotoxin S6d (STX-b) is a peptide toxin isolated from the venom of the Israeli burrowing asp. It induces various Electrocardiogram (ECG) changes such as myocardial ischemia and hyperkalemia. In rat aortas, Sarafotoxin S6d causes intense vasoconstriction dependent on extracellular calcium ions and...
| Keywords: | STX-b |
| MW: | 2591.98 D |
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