Peptides

A derivative of hGHRH (1-44), increases serum levels of IGF-1 in growing pigs at 20 µg/kg twice daily, increases serum levels of growth hormone and IGF-1 in rats and dogs. SMILES:...

A peptide-dye conjugate for the visualization of intact and degenerated nerves, ex/em = 488/530 nm, respectively, has been used to identify degenerated nerves via real-time fluorescence imaging in mice in a model of facial nerve transection at 900 nmol/animal. SMILES:...

An intermediate in the synthesis of cyclo(Delta-Ala-L-Val). SMILES: O=C([C@@H](N1)CO)N[C@@H](C(C)C)C1=O. InChi Code: InChI=1S/C8H14N2O3/c1-4(2)6-8(13)9-5(3-11)7(12)10-6/h4-6,11H,3H2,1-2H3,(H,9,13)(H,10,12)/t5-,6-/m0/s1. InChi Key: NJFKZURMUGDZGV-WDSKDSINSA-N

A peptide fusion tag, inhibits binding of the protein A Z domain to IgG Fc (Ki = 25 nM), can be added to the N- or C-terminus of a protein sequence and has been used as an epitope tag on recombinant proteins to facilitate their detection and purification, inclusion of FcIII peptide increases recombinant protein...

Protein Function: Counteracts the host antiviral immune response when activated and phosphorylated, by preventing host IRF3 from entering the nucleus (PubMed:15452220). Also inhibits the type I interferon production by inactivating the enzymatic activity of DNA sensor CGAS without affecting STING1 (PubMed:29263269)....

Protein Function: Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M (PubMed:33264373). Plays an important role in enhancing the efficiency of subgenomic viral...

Protein Function: Plays a key role in the activation of the host resting B-cell and stimulation of B-cell proliferation. Acts by up-regulating the expression of viral EBNA1-6, LMP1, LMP2A and LMP2B genes, as well as several host genes including CD21, CD23 and MYC. Activates transcription by acting as an adapter...

Protein Function: Required for extrapulmonary dissemination. Mediates adherence to epithelial cells by binding to sulfated glycoconjugates present at the surface of these cells, binds heparin, dextran sulfate, fucoidan and chondroitin sulfate. Promotes hemagglutination of erythrocytes of certain host species....

Protein Function: Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as...

Protein Function: Plays a major role in RD1-associated pathogenesis, and may contribute to the establishment and maintenance of M.tuberculosis infection. Together with PE35, stimulates the secretion of IL-10 and MCP-1 from human macrophages, via the interaction with human Toll-like receptor 2 (TLR2)...

Protein Function: May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization [The Uniprot Consortium]