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Skeletal muscle-targeted peptide MSP
Item number: TGM-TP2841-10mg
Description: Skeletal muscle-targeted peptide MSP, a muscle-targeting peptide (MTP) composed of seven amino acids (ASSLNIA), selectively binds to various ligands in muscle tissues. This targeting capability makes it a useful tool in researching cardiac and skeletal muscle diseases. Target: Others. Smiles:...
| MW: | 674.74 D |
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P17 Peptide
Item number: TGM-TP2844-10mg
Description: P17 Peptide, a human TGF-beta1 inhibitory peptide, effectively blocks the activity of woodchuck TGF-beta1. Target: TGF-beta/Smad. Smiles:...
| MW: | 1995.29 D |
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hsBCL9CT-24
Item number: TGM-TP2866-10mg
Description: hsBCL9CT-24 serves as an inhibitor of the Wnt/beta-catenin (beta-cat) pathway and exhibits significant antitumor effects. This compound reactivates the anticancer immune response that is suppressed by the carcinogenic Wnt pathway, making it valuable for cancer research. Smiles:...
| MW: | 1459.82 D |
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Ub4ix
Item number: TGM-TP2873-10mg
Description: Ub4ix, a DUB/26S proteasome inhibitor, safeguards K48-linked Ub chains against cleavage by deubiquitinating enzymes (DUBs) and inhibits the proteasomal degradation of Ub-tagged proteins. Additionally, it diminishes the viability of Hela cells and triggers apoptosis, exhibiting an IC 50 value of 1.6 µM....
| MW: | 1767.91 D |
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Macrophage-activating lipopeptide 2 TFA
Item number: TGM-TP2905-10mg
Description: Macrophage-activating lipopeptide 2 TFA (MALP-2 TFA) is a diacylglycerol lipopeptide and TLR-2/TLR-6 agonist that activates immune cell responses such as macrophages, upregulating TNF, IL-6, and PGE2 to induce local inflammation. Target: IL Receptor, TLR, TNF, Prostaglandin Receptor. Smiles:...
| Keywords: | MALP-2 TFA |
| MW: | 2135.56 D |
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NDI-Lyso
Item number: TGM-TP2920-10mg
Description: NDI-Lyso is an anticancer agent targeting lysosomes, functioning through an enzyme-induced self-assembly (EISA) mechanism catalyzed by Cathepsin B. In cancer cell lysosomes, it forms rigid long fibers, promoting lysosomal swelling, lysosomal membrane permeabilization (LMP), and membrane disruption. This...
| MW: | 1469.69 D |
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Tasiamide B
Item number: TGM-TP2927-10mg
Description: Tasiamide B is a linear peptide and Cathepsin D inhibitor discovered in the marine cyanobacterium Symploca sp. This compound serves as an excellent template for the development of aspartic protease inhibitors. Tasiamide B effectively targets skin cancer through its strong interaction with the protein...
| MW: | 979.17 D |
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RAWVAWR-NH2
Item number: TGM-TP2928-10mg
Description: RAWVAWR-NH2 is a peptide derived from human lysozyme, exhibiting antibacterial activity. Smiles: C([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)=O)C)=O)C(C)C)=O)NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)C)=O)C=3C=4C(NC3)=CC=CC4
| MW: | 943.11 D |
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MD01-67
Item number: TGM-TP2936-10mg
Description: MD01-67 is a macrocyclic compound selectively targeting the neurotensin 2 receptor (NTS2), with a Ki of 2.9 nM. It exhibits analgesic activity and reduces tactile hypersensitivity in rat models of acute, sustained, and chronic inflammatory pain. Target: Neurotensin Receptor. Smiles:...
| MW: | 742.91 D |
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BIO-11006
Item number: TGM-TP2944-10mg
Description: BIO-11006 Inhibitor is a nebulized 10-amino acid peptide compound that inhibits the protein kinase C substrate known as myristoylated alanine-rich C-kinase substrate (MARCKS) protein, offering potential immunoregulatory and antitumor activities. Smiles:...
| Keywords: | BIO11006 , BIO 11006 |
| MW: | 1050.17 D |
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AC-SDKP-NH2
Item number: TGM-TP2945-10mg
Description: Ac-SDKP is a natural tetrapeptide with anti-inflammatory and anti-fibrotic properties. Smiles: C([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)CO)=O)CC(O)=O)=O)CCCCN)(=O)N1[C@H](C(N)=O)CCC1
| Keywords: | AC-SDKP NH2 , N-Acetyl-L-seryl-L-alpha-aspartyl-L-lysyl-L-prolinamide , AC-SDKP , AC SDKP-NH2 |
| MW: | 486.52 D |
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APL180
Item number: TGM-TP2954-10mg
Description: APL180 (L-4F) is an apolipoprotein A-I mimetic peptide that enhances the anti-inflammatory activity of high-density lipoprotein (HDL). It is applicable for cardiovascular disease research. Target: Apolipoprotein. Smiles:...
| Keywords: | L-4F |
| MW: | 2310.6 D |
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