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HBP08
Item number: TGM-TP2661-10mg
Description: HBP08 is a selective inhibitor that disrupts the interaction between CXCL12 and HMGB1. It demonstrates a high affinity for HMGB1 with a dissociation constant (K d) of 0.8 µM and effectively inhibits cell migration induced by CXCL12. Smiles:...
| MW: | 1260.36 D |
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p53 (232-240)
Item number: TGM-TP2662-10mg
Description: p53 (232-240), a peptide derived from the 232-240 amino acid sequence of the human tumor suppressor protein p53, improves its binding affinity to the Major Histocompatibility Complex (MHC). This enhancement increases the immunogenicity of the peptide, boosting the immune system's response to tumor...
| MW: | 1066.3 D |
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WEYIPNV
Item number: TGM-TP2668-10mg
Description: WEYIPNV is a ligand of SurA, specifically binding to the P1 domain of SurA (Kd: 1-14 µM). Its binding facilitates the release of the P1 domain from the core domain. Smiles:...
| MW: | 920.02 D |
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KGYY15
Item number: TGM-TP2671-10mg
Description: KGYY15 (Mouse KGYY15), a peptide that targets CD40, exhibits weak inhibition of the CD40-CD40L interaction, with an IC50 exceeding 1 mM. At a concentration of 100 µM, KGYY15 activates the NF-kappaB pathway by 33%. Target: TNF. Smiles:...
| Keywords: | KGYY15 peptide , Mouse KGYY15 |
| MW: | 1817.12 D |
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His-Cys-Lys-Phe-Trp-Trp
Item number: TGM-TP2672-10mg
Description: His-Cys-Lys-Phe-Trp-Trp functions as an inhibitor of the human immunodeficiency virus (HIV) integrase, exhibiting an IC50 value of 2 µM. Target: HIV Protease. Smiles:...
| MW: | 906.06 D |
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HIV gp120 (318-327)
Item number: TGM-TP2676-10mg
Description: HIVgp120 (318-327) is a short sequence (rgpgrafvti) from the envelope peptide of the HIV-1 IIIB strain, corresponding to the conserved C-terminal region of the glycoprotein. It is part of the HIV vaccine V3 peptide epitope, also known as the I10 peptide. However, HIVgp120 (318-327) lacks the A2 anchor...
| MW: | 1073.25 D |
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BM30
Item number: TGM-TP2677-10mg
Description: BM30, a peptide mimic, serves as a selective inhibitor of NTMT1 and NTMT2, with an IC50 value of 0.89 µM for NTMT1. Target: DNA Methyltransferase. Smiles: C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CCCCN)(=O)[C@H]1N(C(CC2=CC=C(O)C=C2)=O)CCC1
| MW: | 532.64 D |
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AEC5
Item number: TGM-TP2678-10mg
Description: AEC5 is a lipopeptide compound with antifungal properties effective against Cryptococcus neoformans infections. At its minimum inhibitory concentration (MIC) of 6.3 µg/mL against Cryptococcus neoformans, AEC5 displays no significant cytotoxicity to human lung, liver, or red blood cells. Target:...
| MW: | 521.74 D |
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DP32
Item number: TGM-TP2681-10mg
Description: DP32 is a dual-function compound incorporating an opioid receptor (MOP) agonist and a neuropeptide FF receptor (NPFFR) antagonist. It is applicable in analgesia-related research. Target: Opioid Receptor, Neuropeptide FF Receptor. Smiles:...
| MW: | 1056.3 D |
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ERalpha17p
Item number: TGM-TP2682-10mg
Description: ERalpha17p (ERalpha 295-311), the epitope of the CaM binding site located on estrogen receptor alpha (ER), interacts with calmodulin (CaM) in a calcium-dependent fashion. This peptide is involved in regulating the migration of various cancer cell lines including MCF-7, SK-BR-3, T47D, and MDA-MB-231 via...
| Keywords: | ERalpha (295-311) |
| MW: | 1900.33 D |
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BMAP 28 (bovine)
Item number: TGM-TP2686-10mg
Description: BMAP 28, bovine, is an antimicrobial peptide. It demonstrates antibacterial activity against both Gram-positive and Gram-negative bacteria by increasing cell membrane permeability and causing leakage of cell contents. Furthermore, BMAP 28, bovine, exhibits cytotoxic effects on cancer cells and activated...
| MW: | 3131.85 D |
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d-(KLAKLAK)2, Proapoptotic Peptide
Item number: TGM-TP2687-10mg
Description: d-(KLAKLAK)2 is an antimicrobial and antitumor peptide, notable within the group of antimicrobial peptides, and exhibits strong anticancer properties. It kills bacteria by disrupting their cell membranes, causing leakage of cell contents. Additionally, d-(KLAKLAK)2 inhibits tumor cell proliferation by...
| MW: | 1523.01 D |
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