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APP-018
Item number: TGM-TP2982-10mg
Description: APP-018 (D-4F) is an 18 D-amino acid peptide that mimics apolipoprotein A-I (apoA-I). It enhances the anti-inflammatory properties of high-density lipoprotein (HDL) and is applicable in cardiovascular disease research. Target: Apolipoprotein. Smiles:...
| Keywords: | D-4F |
| MW: | 2310.6 D |
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KRL74
Item number: TGM-TP2983-10mg
Description: KRL74 is a cyclic peptide inhibitor that interferes with the interaction between the p6 domain of the HIV Gag protein and the UEV domain of the human TSG101 protein (p6/UEV), with an IC50 of 5.44 µM and a Kd of 11.9 µM. It also inhibits the budding of HIV from host cells, exhibiting an IC50 of 2 µM in...
| MW: | 981.53 D |
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SVS-1 peptide
Item number: TGM-TP2985-10mg
Description: SVS-1 peptide is an anticancer peptide that selectively targets cancer cells through electrostatic interactions, disrupting the cell membrane structure and inducing cell death. Unlike antimicrobial peptides, the activity of SVS-1 peptide occurs before the complete neutralization of membrane charges....
| MW: | 2031.66 D |
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GNQWFI
Item number: TGM-TP2994-10mg
Description: GNQWFI, an anti-Flt1 peptide, functions as a VEGFR1-specific antagonist. It inhibits interactions between VEGFR1 and various ligands, such as VEGFA, VEGFB, and placental growth factor (PIGF), and suppresses VEGF-induced endothelial cell migration and tubulogenesis. GNQWFI holds potential for research in...
| MW: | 763.84 D |
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4-Amino-D-phenylalanine
Item number: TGM-TP2995-10mg
Description: 4-Amino-D-phenylalanine ([D-Phe(4-NH2)]) is a cyclic pentapeptide that inhibits the binding of CXCL12 to CXCR4 in FC131, with an IC50 value of 0.1 µM. Target: CXCR. Smiles: C([C@H](C(O)=O)N)C1=CC=C(N)C=C1
| Keywords: | 4-NH2-d-Phe |
| MW: | 180.2 D |
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Octaarginine
Item number: TGM-TP3000-10mg
Description: Octaarginine is a cell-penetrating peptide (CPP) known for its membrane-translocating activity. CPP's inherent ability to enter cells makes it useful for delivering various membrane-impermeable bioactive agents intracellularly. Additionally, CPP is employed to transport antimicrobial agents into...
| MW: | 1267.5 D |
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Aselacin C
Item number: TGM-TP3006-10mg
Description: Aselacin C is a cyclic peptide that can be isolated from fungi of the Acremonium spp. Target: Others. Smiles: O=C1OC(C)C(NC(=O)C(NC(=O)CCCCCCCC(=O)C=CC=CCCCCC)CCC(=O)N)C(=O)NCCC(=O)NC(C(=O)NC(C(=O)NC1)CO)CC2=CNC=3C=CC=CC32
| MW: | 907.06 D |
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PIC1 PA
Item number: TGM-TP3013-10mg
Description: PIC1 PA, a peptide consisting of 15 amino acids, serves as an effective analog of PIC1 that inhibits complement activation mediated by the classical pathway. Functionally, PIC1 PA interferes with the interaction between the C1s-C1r-C1r-C1s/MASPs and the collagen-like region (CLR) of C1q/MBL. It...
| MW: | 1642.98 D |
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PGD97
Item number: TGM-TP3018-10mg
Description: PGD97 is a selective cyclic peptide inhibitor targeting the CAL/CFTR interaction, with its desulfurization-cyclized form exhibiting a KD value of 6 nM for the CAL PDZ domain. It shows a selectivity of at least 130-fold over the NHERF1/2 PDZ domains. PGD97 stabilizes F508del-CFTR on the cell membrane,...
| MW: | 1643.01 D |
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GPLGLAGGWGERDGS
Item number: TGM-TP3038-10mg
Description: GPLGLAGGWG ERDGS is a polypeptide with MMP enzyme responsiveness and tumor-targeting properties, suitable for research on enzyme-guided nanoparticle assembly within tumors. Target: MMP. Smiles:...
| MW: | 1428.51 D |
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ED11
Item number: TGM-TP3043-10mg
Description: ED11 is a potent and selective caspase-6 inhibitor with an IC50 of 12.12 nM. It competes with Htt for the caspase-6 active site, thereby reducing Htt cleavage. ED11 is capable of crossing the blood-brain barrier (BBB) and holds potential for researching Huntington's disease (HD). Target: Caspase....
| MW: | 2850.16 D |
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LH2 peptide
Item number: TGM-TP3047-10mg
Description: LH2 peptide is a pH-responsive, cell-penetrating peptide dimer with the amino acid sequence LHHLCHLLHH LCHLAG. It increases uptake in tumor cells in slightly acidic environments (such as the tumor microenvironment) through histidine residue protonation (pKa approximately 6). When conjugated with the...
| MW: | 1854.21 D |
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