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Item number: TGM-TP2806-10mg
Description: PKA Regulatory Subunit II Substrate (RII phosphopeptide) is a tool peptide derived from the regulatory subunit Type II (RII) of cyclic adenosine monophosphate-dependent protein kinase (PKA). It is commonly used to simulate the phosphorylation activity of protein kinases and to assess the activity of...
| Keywords: | RII phosphopeptide |
| MW: | 2192.32 D |
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Item number: TGM-TP2810-10mg
Description: [Tyr6,D-Phe7,D-His9]-Substance P (6-11) is a tachykinin NK1 receptor antagonist that can counteract histamine-induced hyperalgesia. Smiles: [C@H](CC1=CC=CC=C1)(C(N[C@H](CC2=CN=CN2)C(N[C@H](C(N[C@@H](CCSC)C(N)=O)=O)CC(C)C)=O)=O)NC([C@@H](CC3=CC=CC=C3)NC([C@H](CC4=CC=C(O)C=C4)N)=O)=O
| MW: | 856.04 D |
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Item number: TGM-TP2812-10mg
Description: T9 peptide (SKTFNTHPQS TP) is a muscle-targeting peptide that tightly binds to C2C12 myoblasts. When combined with oligonucleotides, T9 peptide enhances specificity towards the heart and quadriceps without similarly targeting the kidney, liver, or diaphragm. Smiles:...
| MW: | 1344.43 D |
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Item number: TGM-TP2819-10mg
Description: BIMAX2 is a high-affinity peptide for nuclear localization signals (NLS). It mimics the activity of classical nuclear localization signals (cNLS) by competitively binding to importin alpha, thereby inhibiting the interaction between cNLS-cargo proteins and importin alpha. BIMAX2 is utilized in studies...
| MW: | 3561.98 D |
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Item number: TGM-TP2817-10mg
Description: Myr-Arf1(2â?"17) is a myristoylated peptide utilized to simulate the localization and function of the Arf1 protein on the cell membrane. This compound is also employed in investigating the desensitization mechanisms of the luteinizing hormone/chorionic gonadotropin receptor (LH/CGR). Smiles:...
| MW: | 1993.43 D |
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Item number: TGM-TP2818-10mg
Description: Salusin-beta, an endogenous bioactive peptide, exhibits significant hemodynamic and mitotic activities. It can stimulate the proliferation of quiescent vascular smooth muscle cells (VSMCs) and fibroblasts, leading to a rapid and marked decrease in blood pressure and heart rate. Additionally, in rat...
| MW: | 2342.83 D |
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Item number: TGM-TP2820-10mg
Description: (Z-LL)2 ketone, an inhibitor of ketone with an IC50 value of 50 nM, facilitates the release of N-terminal fragments into the cytoplasm. Smiles: [C@H](C(N[C@H](C(NCC(CNC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(C)C)=O)CC(C)C)=O)=O)=O)CC(C)C)=O)(NC(OCC2=CC=CC=C2)=O)CC(C)C
| MW: | 809 D |
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Item number: TGM-TP2822-10mg
Description: SHLP-5, a mitochondrial-derived peptide, is encoded by the MT-RNR2 gene which produces a bioactive microprotein. This compound is utilized in researching diabetes, Alzheimers disease, cardiovascular diseases, and prostate cancer. Smiles:...
| MW: | 2565.93 D |
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Item number: TGM-TP2828-10mg
Description: Tetanus toxin peptide, a specific peptide segment isolated from the toxin produced by Clostridium tetani, serves as an immunogen in mice to induce diabetes. It is also utilized in the research of Type 1 diabetes. Smiles:...
| MW: | 1657.91 D |
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Item number: TGM-TP2836-10mg
Description: Pepinh-MYD, a MyD88 inhibitor, incorporates both a domain sequence from MyD88 TIR and a protein transduction sequence to facilitate cell membrane penetration. This compound disrupts MyD88-mediated TLR signaling pathways, effectively inhibiting associated immune responses. Its design is particularly...
| MW: | 3388.03 D |
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Item number: TGM-TP2839-10mg
Description: IMG-2005 acts as an inhibitor of the TLR signaling pathway by mimicking the Toll/interleukin-1 receptor (TIR) domain of MyD88. This action prevents the homodimerization of MyD88, mitigating damage to tracheal epithelial cells and averting the onset of pulmonary immune diseases. Smiles:...
| MW: | 3100.65 D |
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Item number: TGM-TP2846-10mg
Description: The HiBiT tag, a complementary peptide (VSGWRLFKKIS), exhibits high affinity for LgBiT. It is fused with the Gbeta subunit of the receptor. The interaction between LgBiT and HiBiT facilitates the stabilization of ETR and G proteins. Additionally, HiBiT can be attached to target proteins (GFP) to...
| MW: | 1320.58 D |
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