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Item number: TGM-TP2666-10mg
Description: Compound Q6 (Insecticidal agent 11) serves as a potent insect growth regulator (IGR)-based insecticide, effectively inhibiting juvenile hormone (JH) biosynthesis to control Diploptera punctata. Furthermore, it demonstrates significant insecticidal activity against Plutella xylostella. Target: Parasite....
| MW: | 623.66 D |
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Item number: TGM-TP2673-10mg
Description: TAT-PiET, a cell-penetrating peptide, targets the extra-terminal (ET) domain of BRD4, disrupting the critical BRD4/JMJD6 protein complex interaction necessary for oncogene expression in breast cancer. By inhibiting BRD4/JMJD6 target gene expression, TAT-PiET effectively suppresses breast cancer cell...
| MW: | 2651.07 D |
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Item number: TGM-TP2683-10mg
Description: CaMKI (299-320) is a peptide representing residues 299-320 of Calcium/calmodulin-dependent protein kinase I (CaMKI). This segment, functioning as a protein kinase, exhibits a strong interaction with Ca 2+ -CAM (K d â%¤1 nM), enabling it to phosphorylate specific substrate proteins and regulate their...
| Keywords: | Calmodulin-Dependent Protein Kinase I (299-320) Binding Domain |
| MW: | 2599.07 D |
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Item number: TGM-TP2684-10mg
Description: Tiger17 is a potent wound healing agent that stimulates the secretion of TGF-beta1 and operates via the Smad signaling pathway. It specifically enhances wound repair by increasing the phosphorylation of Smad2 and Smad3. As a polypeptide facilitating endogenous healing, Tiger17 serves as a valuable tool...
| MW: | 1378.71 D |
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Item number: TGM-TP2688-10mg
Description: PKCdelta substrate serves as a nuclear transport protein for ERK2 and is involved in ERK2-mediated gene activation. PKCdelta plays a role in regulating cellular growth, proliferation, cell cycle arrest, and apoptosis by phosphorylating hBVR and other proteins. The PKCdelta substrate can be used in...
| MW: | 1529.75 D |
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Item number: TGM-TP2691-10mg
Description: Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp serves as a fluorescence-quenched peptide substrate specifically designed for the enzyme human proteinase 3 (k cat /K m = 1,570 mM -1 s -1 ). It is utilized to detect the activity of proteinase 3 (PR3). Smiles:...
| MW: | 1285.33 D |
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Item number: TGM-TP2692-10mg
Description: Ser-Ala-Pro is a specific X-Pro structured angiotensin-converting enzyme (ACE) inhibitory peptide. It shows potential for use in hypertension research. Target: Angiotensin-converting Enzyme (ACE). Smiles: C([C@@H](NC([C@H](CO)N)=O)C)(=O)N1[C@H](C(O)=O)CCC1
| MW: | 273.29 D |
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Item number: TGM-TP2695-10mg
Description: Braftide is an allosteric inhibitor of BRAF kinase that exerts its effect by targeting the surface of BRAF kinase dimers, thereby preventing their formation. It inhibits both wild-type BRAF and oncogenic BRAFG469A, with IC50 values of 364 nM and 172 nM, respectively. When combined with the TAT sequence,...
| MW: | 1243.52 D |
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Item number: TGM-TP2696-10mg
Description: S-palm P0(180â?"199) is a peptide that can enhance MHC II class-restricted responses and is applicable in developing models of chronic inflammatory demyelinating polyneuropathy (CIDP). Smiles: C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CSC(CCCCCCCCCC...
| MW: | 2528.05 D |
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Item number: TGM-TP2707-10mg
Description: Azaline B is an antagonist of the gonadotropin-releasing hormone (GnRH), with an IC50 of 1.37 nM. It is utilized in research related to pathologies associated with sex hormones, ovulation induction, and male contraception. Target: GNRH Receptor. Smiles:...
| MW: | 1613.27 D |
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Item number: TGM-TP2708-10mg
Description: Multi-Leu peptide (ML-peptide), with a K i value of 22 nM, acts as a potent inhibitor of PACE4 by competitively binding to its active site and mimicking its substrate sequence, thus suppressing the enzyme's catalytic function. This compound is useful for investigating PACE4's specific role in the...
| Keywords: | ML-peptide, Multi-Leucine (ML)-peptide |
| MW: | 1051.37 D |
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Item number: TGM-TP2709-10mg
Description: SHAAGtide is an FPRL1 activator with anti-inflammatory properties. It exerts its biological activity through FPR2 and has been utilized in mouse models to reduce the expression of inflammatory cytokines. SHAAGtide is applicable in research on conditions such as pulmonary inflammation and fibrosis....
| MW: | 2053.46 D |
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