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LAH4
Item number: TGM-TP1811-10mg
Description: The a-helix of the amphipathic peptide antibiotic LAH4 (KKALLALALH HLAHLALHLA LALKKA-NH2) strongly interacts with phospholipid membranes, demonstrating in vitro transfection efficiencies comparable to those of commercially available reagents. References: Perrone B, et al. Lipid interactions of LAH4, a...
| MW: | 2779.53 D |
From 110.00€
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Urotensin II, mouse
Item number: TGM-TP1816-10mg
Description: Jump to search UTS2 Identifiers Aliases UTS2, PRO1068, U-II, UCN2, UII, urotensin 2 External IDs OMIM: 604097 MGI: 1346329 HomoloGene: 4939 GeneCards: UTS2 hide Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.23 Start 7,843,083 bp[1] End 7,853,512 bp[1] show Gene location (Mouse) hide RNA...
| CAS | 9047-55-6 |
| MW: | 1633.86 D |
From 139.00€
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LL-37 scrambled peptide
Item number: TGM-TP1825-1mg
Description: LL-37 scrambled peptide is a rearranged version of the cathelicidin anti-microbial peptide (LL-37).
| MW: | 4493.3 D |
From 198.00€
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[Ala92]-p16 (84-103)
Item number: TGM-TP2133-1mg
Description: Peptide derived from the tumor suppressor protein p16, inhibits cyclin-dependent kinase-4 (cdk4)/cyclin D1 (IC50 ~ 1.5 µM) and binds to cdk6. References: Fahraeus et al (1998) Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour...
| CAS | 189064-08-2 |
| MW: | 2123.44 D |
189.00€
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c-JUN peptide
Item number: TGM-TP2134-1mg
Description: Peptide comprising residues 33 - 57 of the JNK binding (delta) domain of human c-Jun. Disrupts JNK/c-Jun interaction leading to inhibition of serum-induced c-Jun phosphorylation, up-regulation of p21cip/waf and modulation of inflammatory gene expression. Specifically induces apoptosis in HeLa tumor...
| CAS | 610273-01-3 |
| MW: | 2743.55 D |
1,004.00€
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cAC 253
Item number: TGM-TP2135-5mg
Description: Amylin (AMY3) antagonist (IC50 = 0.3 µM). Protects neuronal cells from Abeta(1-42)-induced cytotoxicity in vitro. Brain penetrant. Improves spatial memory and reduces Abeta plaque number and total area in a mouse Alzheimer's disease model. References: Soudy et al (2016) Cyclic AC253, a novel amylin...
| MW: | 3009.36 D |
672.00€
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(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin
Item number: TGM-TP2136-1mg
Description: Selective vasopressin V1A receptor antagonist. Inhibits vasopressin and oxytocin-induced increases in intracellular calcium concentrations in vitro (IC50 values are 5 and 30 nM respectively). Exhibits potent and prolonged antivasopressor activity and induces anxiolytic-like effects in the dorsal, but...
| CAS | 73168-24-8 |
| MW: | 1151.38 D |
627.00€
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pp60 c-src (521-533) (phosphorylated)
Item number: TGM-TP2137-10mg
Description: Peptide corresponding to the pp60c-src carboxy terminal regulatory domain, phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potential. References: Harder et al (1994) Characterization and kinetic analysis of the...
| CAS | 149299-77-4 |
| MW: | 1543.5 D |
426.00€
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st-Ht31
Item number: TGM-TP2138-1mg
Description: Stearated form of the peptide Ht-31. Inhibits the interaction between the RII subunits of cAMP-dependent PKA and A-kinase anchoring protein (AKAP) in cell extracts. Cell permeable. References: Gorshkov et al (2017) AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons....
| CAS | 188425-80-1 |
| MW: | 2798.27 D |
815.00€
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Balixafortide TFA (1051366-32-5 free base)
Item number: TGM-TP2141-100mg
Description: Balixafortide TFA (POL6326 TFA) is a selective, well-tolerated peptidic CXCR4 antagonist (IC50 < 10 nM). It shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide TFA blocks beta-arrestin recruitment and calcium flux (IC50s < 10 nM). Target: CXCR. References:...
| Keywords: | POL6326 TFA, Balixafortide TFA |
| MW: | 1896.05 D |
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CLIP (86-100) (TFA) (648881-58-7 free base)
Item number: TGM-TP2142-100mg
Description: CLIP (86-100) TFA is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen-binding groove. Target: Others. References: van Luijn MM, et al. Class II-associated...
| Keywords: | CLIP (86-100) (TFA) |
| MW: | 1788.13 D |
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Endothelin-2 (49-69), human TFA
Item number: TGM-TP2143-100mg
Description: Endothelin-2 (49-69), human (TFA), is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB receptors. Target: Others. References: Grimshaw MJ, et al. Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors. Eur J Immunol. 2002 Sep,32(9):2393-400.
| Keywords: | Endothelin-2 (49-69) (human, canine) TFA, Human endothelin-2 TFA |
| MW: | 2660.94 D |
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