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Zilucoplan TFA
Item number: TGM-T80083-50mg
Description: Zilucoplan TFA (RA101495), a 15-amino acid macrocyclic peptide, is a potent inhibitor of complement component 5 (C5) with applications in studying immune-mediated necrotising myopathy (IMNM) [1] [2]. Target: Complement System
| Keywords: | RA101495 TFA |
| MW: | 3562.18 D |
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[DPro10] Dynorphin A (1-11), porcine hydrochloride
Item number: TGM-T80085-50mg
Description: [DPro10] Dynorphin A (1-11), porcine hydrochloride, is an N-alkylated derivative and potent kappa-opioid receptor agonist with a K i value of 0.13 nM, possessing analgesic properties [1] [2].
| MW: | 1362.62 D |
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DALDA TFA
Item number: TGM-T80086-50mg
Description: DALDA TFA is a potent, µ-opioid receptor agonist exhibiting high selectivity and an affinity constant (K i) of 1.69 nM. It demonstrates antinociceptive properties and influences respiratory functions [1]. Target: Opioid Receptor
| MW: | 611.74 D |
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(Leu31,Pro34)-Peptide YY (human) (TFA)
Item number: TGM-T80087-50mg
Description: "(Leu31,Pro34)-Peptide YY (human) (TFA) is the trifluoroacetic acid (TFA) form of (Leu31,Pro34)-Peptide YY (human), a derivative of Peptide YY that acts as a potent and selective Y1 agonist, exhibiting a dissociation constant (K D) of 1.0 nM [1].". Target: Neuropeptide Y Receptor
| MW: | 4292.75 D |
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IETD-CHO TFA
Item number: TGM-T80093-50mg
Description: IETD-CHO TFA (Caspase-8-IN-1) functions as a potent inhibitor of caspase-8 [1]. Target: Caspase
| MW: | 2000.42 D |
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Tamapin TFA
Item number: TGM-T80171-50mg
Description: Tamapin TFA, a venom peptide isolated from the Indian red scorpion (Mesobuthus tamulus) [1], selectively targets and blocks small conductance Ca(2+)-activated K(+) (SK) channels, particularly the SK2 subtype (Potassium Channel). It is known to inhibit SK channel-mediated currents in the hippocampal...
| MW: | 3458.11 D |
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TAT-BH4 (Bcl-xL) (TFA)
Item number: TGM-T80222-50mg
Description: "TAT-BH4 (Bcl-xL) TFA, primarily localized at the mitochondria, inhibits apoptotic cell death. This compound comprises an eosin-labeled cysteine at the N-terminal and the protein transduction domain from the HIV TAT protein (amino acids 49 to 57), fused to the Bcl-xL BH4 peptide. It is utilized in...
| MW: | 3712.19 D |
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NODAGA-LM3 TFA
Item number: TGM-T80238-50mg
Description: NODAGA-LM3 TFA, a SSTR2 antagonist, can be radiolabeled with ^68Ga for PET imaging applications, particularly in the visualization of SSTR-positive paragangliomas [1] [2].
| MW: | 1521.11 D |
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A8SGLP-1 TFA
Item number: TGM-T80306-50mg
Description: A8SGLP-1 TFA, an orally active GLP-1 analogue, features a serine substitution for alanine at position 8. This compound effectively lowers blood glucose in db/db mice, maintaining its function [1].
| MW: | 3370.68 D |
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TAT-NEP1-40 TFA
Item number: TGM-T80419-50mg
Description: TAT-NEP1-40 TFA, a blood-brain barrier-permeable peptide, safeguards PC12 cells against oxygen and glucose deprivation (OGD) and fosters neurite outgrowth. Additionally, it enhances neurological outcomes post-ischemia by curtailing apoptosis in ischemic cerebral tissues. This compound has utility in...
| MW: | 6124.89 D |
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TAT-NEP1-40 acetate
Item number: TGM-T80420-50mg
Description: TAT-NEP1-40 acetate, a potential therapeutic for axonal regeneration and functional recovery post-stroke, safeguards PC12 cells from oxygen and glucose deprivation (OGD) and encourages neurite outgrowth. This compound also affords cerebral protection against ischemia/reperfusion injury by hindering...
| MW: | 6124.89 D |
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Phoenixin-20 TFA
Item number: TGM-T80424-50mg
Description: Phoenixin-20 (TFA) (PNX-20 (TFA)) is a bioactive peptide that stimulates hypothalamo-pituitary-gonadal hormones, regulates mammalian reproductive processes, enhances neuronal mitochondrial biogenesis via the CREB-PGC-1alpha pathway, and exhibits anxiolytic properties [1] [2] [3]. Target: Epigenetic...
| Keywords: | PNX-20 TFA |
| MW: | 2181.45 D |
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