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µ-Conotoxin BuIIIB
Item number: TGM-T80491-50mg
Description: µ-Conotoxin BuIIIB (Mu-Conotoxin BuIIIB), derived from cone snail venom, is a selective blocker of mammalian neuronal voltage-gated sodium channels (VGSC) and is used as a research probe for ion channel function and the investigation of neurological disorders like pain [1]. Target: Sodium Channel
| Keywords: | Mu-Conotoxin BuIIIB |
| CAS | 1400096-06-1 |
| MW: | 2763.18 D |
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Mambalgin-2
Item number: TGM-T80492-50mg
Description: Mambalgin-2 (Mamb-2), a venom peptide sourced from the African black mamba, acts as an inhibitor of acid-sensitive ion channels (ASICs). It is utilized in research focused on pain and neurological diseases [1]. Target: Sodium Channel
| Keywords: | Mamb-2 |
| MW: | 6540.5 D |
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µ-Conotoxin BuIIIA
Item number: TGM-T80493-50mg
Description: µ-Conotoxin BuIIIA (Mu-Conotoxin BuIIIA), derived from cone snail venom, functions as a voltage-gated sodium channel (VGSC) blocker and is utilized in researching neurological diseases [1]. Target: Sodium Channel
| MW: | 2751.17 D |
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Tap1a
Item number: TGM-T80494-50mg
Description: Theraphotoxin-Tap1a (Tap1a) is a spider venom-derived peptide that acts as an inhibitor of sodium channels, displaying IC50 values of 80 nM for Na v 1.7 and 301 nM for Na v 1.1. It demonstrates analgesic effects [1]. Target: Sodium Channel
| Keywords: | TRTX-Tap1a, µ/omega-TRTX-Tap1a, Theraphotoxin-Tap1a |
| MW: | 4182.68 D |
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mHuwentoxin-IV
Item number: TGM-T80495-50mg
Description: mHuwentoxin-IV, a naturally modified form of Huwentoxin-IV, selectively inhibits tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels in dorsal root ganglion neurons with an IC50 value of 54.16 nM. Notably, the inhibitory effect of mHuwentoxin-IV on these sodium channels is unaffected by strong...
| MW: | 4088.76 D |
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Kurtoxin
Item number: TGM-T80496-50mg
Description: Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor with a dissociation constant (Kd) of 15 nM for the Cav3.1 (alpha1G T-type) Ca2+ channel. It exhibits high-affinity interactions with native neuronal high-threshold L-type, N-type, and P-type Ca2+ channels in both central...
| MW: | 7386.36 D |
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KTX-Sp2
Item number: TGM-T80497-50mg
Description: KTX-Sp2, a potassium channel toxin, effectively blocks exogenous voltage-gated potassium channels Kv1.1, Kv1.2, and Kv1.3, as well inhibits the endogenous Kv1.3 channel and suppresses Ca2+ signaling in Jurkat T cells. Additionally, KTX-Sp2 inhibits IL-2 secretion from activated Jurkat T cells [1]....
| MW: | 3928.41 D |
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Jingzhaotoxin-XII
Item number: TGM-T80498-50mg
Description: Jingzhaotoxin-XII (JzTx-XII) functions as a potent inhibitor of the Kv4.1 channel, exhibiting an inhibitory concentration (IC50) of 0.363 µM. It modulates the channel's gating behavior [1]. Target: Potassium Channel
| Keywords: | JzTx-XII |
| MW: | 3665.23 D |
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Jingzhaotoxin XI
Item number: TGM-T80499-50mg
Description: Jingzhaotoxin XI (JZTX-XI) is a potent inhibitor of sodium conductance with an IC50 of 124 nM, and it significantly delays the rapid inactivation of Na_v1.5, with an EC50 of 1.18±0.2 µM, when expressed in Chinese hamster ovary (CHO-K1) cells [1]. Target: Sodium Channel
| Keywords: | JZTX-XI |
| MW: | 3726.27 D |
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Jingzhaotoxin-X
Item number: TGM-T80500-50mg
Description: Jingzhaotoxin-X (JZTX-X) selectively inhibits Kv4.2 and Kv4.3 potassium channels, resulting in prolonged mechanical hyperalgesia [1]. Target: Potassium Channel
| Keywords: | JZTX-X |
| MW: | 3706.35 D |
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Myr-TAT-CBD3
Item number: TGM-T80501-50mg
Description: Myr-TAT-CBD3, a CRMP2-CaV2.2 interaction inhibitor, has been shown to significantly attenuate carrageenan-induced thermal hypersensitivity and reverse thermal hypersensitivity in a rat model of postoperative pain, making it a useful compound for studying inflammation and postoperative pain [1]. Target:...
| MW: | 3403.09 D |
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P4pal10
Item number: TGM-T80502-50mg
Description: P4pal10, a PAR 4 antagonist, inhibits thrombin-mediated aggregation of mouse platelets in vivo and significantly diminishes Carrageenan-induced edema and granulocyte infiltration [1].
| CAS | 1021346-05-3 |
| MW: | 1409.72 D |
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