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alphaO-Conotoxin GeXIVA
Item number: TGM-T80479-50mg
Description: alphaO-Conotoxin GeXIVA, a potent antagonist of the alpha9alpha10 nicotinic acetylcholine receptor (nAChR), exhibits an inhibition concentration 50 (IC50) of 12 nM against rat alpha9alpha10 nAChRs. This compound has demonstrated analgesic properties in animal pain models [1].
| CAS | 2010167-25-4 |
| MW: | 3452.89 D |
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alphaA-Conotoxin OIVA
Item number: TGM-T80480-50mg
Description: alphaA-Conotoxin OIVA (alphaA-OIVA), a peptide derived from conotoxin, is a selective nAChR antagonist with an IC50 of 56 nM against mammalian fetal muscle nAChR, resulting in muscle paralysis [1] [2].
| Keywords: | alphaA-OIVA |
| CAS | 878027-87-3 |
| MW: | 1848.16 D |
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alpha-Conotoxin Bt1.8
Item number: TGM-T80481-50mg
Description: alpha-Conotoxin Bt1.8 is a potent inhibitor of both rat alpha6/alpha3beta2beta3 and alpha3beta2 neuronal nicotinic acetylcholine receptors (nAChRs), exhibiting half-maximal inhibitory concentrations (IC50s) of 2.1 nM and 9.4 nM, respectively [1].
| MW: | 1645.86 D |
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alpha-Conotoxin EIIB
Item number: TGM-T80482-50mg
Description: Alpha-Conotoxin EIIB is a peptide toxin derived from Conus ermineus that selectively binds to neuronal nicotinic acetylcholine receptors (nAChR) with a dissociation constant (Ki) of 2.2 nM. This compound is utilized in neurological research, including the study of schizophrenia, drug addiction,...
| Keywords: | Alpha-conotoxin EIIB |
| MW: | 1754.99 D |
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Aam-KTX
Item number: TGM-T80483-50mg
Description: Aam-KTX, a toxic peptide sourced from Mesobuthus eupeus scorpion venom, acts as a selective K_v channel inhibitor, exhibiting IC_50 values of 1.1 nM for K_v1.3 channels and >750 nM for K_v1.1 channels. This compound shows promise for research in autoimmune diseases [1]. Target: Potassium Channel
| MW: | 4184.96 D |
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Aa1 toxin
Item number: TGM-T80484-50mg
Description: Aa1 toxin, sourced from Androctonus australis Garzoni venom, is a neurotoxic peptide that specifically blocks potassium channels and has applications in neurological disease research [1]. Target: Potassium Channel
| MW: | 3868.46 D |
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µ-Conotoxin SxIIIC
Item number: TGM-T80485-50mg
Description: µ-Conotoxin SxIIIC, an irreversible NaV channel inhibitor, is derived from Conus striolatus and is useful in researching neurological disorders, including chronic pain [1]. Target: Sodium Channel
| MW: | 2436.75 D |
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alphaA-Conotoxin PIVA
Item number: TGM-T80486-50mg
Description: alphaA-Conotoxin PIVA serves as a selective inhibitor of mouse muscle nicotinic acetylcholine receptors (nAChRs), demonstrating half-maximal inhibitory concentrations (IC50) of 2.3 nM for adult and 22 nM for fetal mouse muscle nAChRs. The compound is utilized in research related to neurological diseases.
| CAS | 171439-59-1 |
| MW: | 2648.89 D |
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MmTx2 toxin
Item number: TGM-T80487-50mg
Description: MmTx2 toxin, extracted from the venom of the coral snake, serves as a modulator of the GABA A receptor, increasing its responsiveness to agonists. This property renders it a useful tool in researching neurological disorders, including epilepsy, schizophrenia, and chronic pain [1]. Target: GABA Receptor
| Keywords: | Micrurotoxin 2 |
| MW: | 7185.95 D |
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µ-Conotoxin SIIIA
Item number: TGM-T80488-50mg
Description: µ-Conotoxin SIIIA, a tetrodotoxin (TTX)-resistant sodium channel blocker, is a toxic peptide derived from Conus snail venom. It has applications in researching neurological diseases, including neuropathic pain [1]. Target: Sodium Channel
| CAS | 877860-32-7 |
| MW: | 2207.46 D |
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MmTx1 toxin
Item number: TGM-T80489-50mg
Description: Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1]. Target: GABA Receptor
| Keywords: | Micrurotoxin 1 |
| MW: | 7205 D |
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µ-Conotoxin BuIIIC
Item number: TGM-T80490-50mg
Description: µ-Conotoxin BuIIIC (Mu-Conotoxin BuIIIC) effectively inhibits the NaV1.4 sodium channel [1]. Target: Sodium Channel
| Keywords: | Mu-Conotoxin BuIIIC |
| CAS | 1400096-08-3 |
| MW: | 3006.44 D |
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