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Boc-AEVD-CHO
Item number: TGM-T80467-50mg
Description: Boc-AEVD-CHO, a selective Caspase 8 inhibitor, facilitates apoptosis research and the investigation of immune and inflammatory diseases [1] [2]. Target: Caspase
| CAS | 220094-15-5 |
| MW: | 516.54 D |
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delta-Dendrotoxin
Item number: TGM-T80468-50mg
Description: delta-Dendrotoxin is a potassium (K+) channel blocker derived from black mamba snake venom and is utilized in neurological disease research [1]. Target: Potassium Channel
| CAS | 189201-23-8 |
| MW: | 6567.65 D |
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Citrullinated LL-37 1cit
Item number: TGM-T80469-50mg
Description: Citrullinated LL-37 1cit, a modified LL-37 peptide, retains the antiviral properties of its parent compound against human rhinovirus and exhibits antibacterial activity against S. aureus. Furthermore, it diminishes the RV1B-induced expression of pro-inflammatory cytokines, including IL-8, CCL5, and IL-6...
| MW: | 4494.25 D |
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Citrullinated LL-37 2cit
Item number: TGM-T80470-50mg
Description: Citrullinated LL-37 2cit, a modified version of the LL-37 peptide, attenuates the antiviral efficacy of LL-37 against Human Rhinovirus (HRV) at a concentration of 10 µg/mL and diminishes its antibacterial properties. Furthermore, the compound diminishes RV1B-induced mRNA expression of pro-inflammatory...
| MW: | 4495.23 D |
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alpha-Conotoxin MrIC
Item number: TGM-T80471-50mg
Description: alpha-Conotoxin MrIC is a biased agonist selective for the alpha7 nicotinic acetylcholine receptor (nAChR), with activation contingent upon the presence of type II positive allosteric modulators, such as PNU120596. It is utilized to investigate neurological disorders and delineate the pharmacological...
| CAS | 1417816-41-1 |
| MW: | 1835.07 D |
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alpha-Conotoxin LtIA
Item number: TGM-T80472-50mg
Description: alpha-Conotoxin LtIA, an alpha3beta2 nAChR blocker with an IC50 value of 9.8 nM, is derived from Conus litteratus venom and is utilized in researching neurological diseases, including Parkinson's disease and pain [1].
| MW: | 1600.87 D |
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Citrullinated LL-37 3cit
Item number: TGM-T80473-50mg
Description: Citrullinated LL-37 3cit is a host defense peptide with notable immunomodulatory and antimicrobial properties, which exhibits direct antiviral activity against human rhinoviruses (HRV) [1]. Target: Influenza Virus
| MW: | 4496.22 D |
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Citrullinated LL-37 4cit
Item number: TGM-T80474-50mg
Description: Citrullinated LL-37 3cit, a modified form of the LL-37 peptide, exhibits no antiviral activity at a concentration of 10 µg/mL while maintaining partial efficacy against HRV at 30 µg/mL. Furthermore, this citrullinated variant demonstrates diminished immunomodulatory properties compared to the native...
| MW: | 4497.2 D |
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alpha-Conotoxin AuIA
Item number: TGM-T80475-50mg
Description: alpha-Conotoxin AuIA, isolated from Conus aulicus [1], is a potent and selective inhibitor of alpha3beta4 nicotinic acetylcholine receptors (nAChRs).
| CAS | 216299-20-6 |
| MW: | 1725.9 D |
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alpha-Conotoxin RgIA
Item number: TGM-T80476-50mg
Description: alpha-Conotoxin RgIA (alpha-RgIA), a specific alpha9alpha10 nAChR antagonist, is derived from the venom of Conus regius and has applications in researching neurological diseases [1].
| Keywords: | alpha-RgIA |
| CAS | 876728-23-3 |
| MW: | 1570.8 D |
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Muscarinic toxin 3
Item number: TGM-T80477-50mg
Description: Muscarinic toxin 3 (MT3), a potent non-competitive antagonist of mAChR and adrenoceptors, exhibits pIC50 values of 6.71 for M1, 8.79 for M4, 8.86 for alpha1A, 7.57 for alpha1B, 8.13 for alpha1D, 8.49 for alpha2A, <6.5 for alpha2B, and 7.29 for alpha2C receptors. MT3 notably demonstrates significant...
| Keywords: | MT3 |
| CAS | 873336-87-9 |
| MW: | 7379.35 D |
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alpha-Conotoxin GIC
Item number: TGM-T80478-50mg
Description: alpha-Conotoxin GIC is a selective and potent antagonist of the alpha3beta2 nicotinic acetylcholine receptor, exhibiting an inhibition constant (IC50) of 1.1 nM [1].
| CAS | 757236-92-3 |
| MW: | 1609.79 D |
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