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omega-Conotoxin CVIB
Item number: TGM-T80455-50mg
Description: omega-Conotoxin CVIB is an antagonist of non-selective N- and P/Q-type voltage-gated calcium channels (VGCCs). It inhibits depolarization-activated whole-cell VGCC currents in dorsal root ganglion (DRG) neurons, exhibiting a pIC50 of 7.64 [1]. Target: Sodium Channel
| CAS | 325164-09-8 |
| MW: | 2710.18 D |
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BDS-II
Item number: TGM-T80456-50mg
Description: BDS-II, a peptide toxin comprising 43 amino acids, selectively inhibits the Kv3.4 channel [1]. Target: Sodium Channel
| MW: | 4776.42 D |
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omega-Conotoxin Bu8
Item number: TGM-T80457-50mg
Description: omega-Conotoxin Bu8 is a 25-amino-acid-residue omega-conotoxin that features three disulfide bridges. It selectively and potently inhibits rat CaV2.2-mediated depolarization-activated Ba2+ currents in HEK293T cells with an IC50 of 89 nM [1]. Target: Calcium Channel
| MW: | 2753.13 D |
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omega-Conotoxin CVIA
Item number: TGM-T80458-50mg
Description: omega-Conotoxin CVIA, a 27-amino acid neuropeptide, functions as a blocker of voltage-sensitive calcium channels (VSCCs) [1]. Target: Calcium Channel
| CAS | 325164-06-5 |
| MW: | 2641.95 D |
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omega-Conotoxin CnVIIA
Item number: TGM-T80459-50mg
Description: omega-Conotoxin CnVIIA, a 27-amino-acid neuropeptide toxin, serves as an N-type calcium current blocker [1]. Target: Calcium Channel
| CAS | 760212-36-0 |
| MW: | 2848.29 D |
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Azemiopsin
Item number: TGM-T80460-50mg
Description: Azemiopsin, a potent inhibitor of the nicotinic acetylcholine receptor (nAChR), demonstrates half maximal inhibitory concentrations (IC50s) of 0.18 µM for T. californica nAChR and 22 µM for human alpha7 nAChR. Moreover, it effectively blocks acetylcholine-induced currents in Xenopus oocytes that...
| CAS | 1391936-86-9 |
| MW: | 2540.88 D |
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Anthopleurin-C
Item number: TGM-T80461-50mg
Description: Anthopleurin-C (APE 2-1) is a cardiotonic polypeptide that exhibits a potent positive inotropic effect [1]. Target: Sodium Channel
| MW: | 4877.52 D |
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kappaM-Conotoxin RIIIK
Item number: TGM-T80462-50mg
Description: kappaM-Conotoxin RIIIK is a potassium channel antagonist that inhibits voltage-activated potassium ion channels [1]. Target: Potassium Channel
| Keywords: | kappaM-RIIIK |
| CAS | 740843-55-4 |
| MW: | 2649.15 D |
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Dynorphin B (1-9)
Item number: TGM-T80463-50mg
Description: Dynorphin B (1-9), a neuropeptide and the N-terminal cleavage product of dynorphin B, has its formation inhibited by N-ethylmaleimide (NEM), a non-selective cysteine peptidase inhibitor [1]. Target: Opioid Receptor
| CAS | 126050-26-8 |
| MW: | 1143.3 D |
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kappaM-Conotoxin RIIIJ
Item number: TGM-T80464-50mg
Description: kappaM-Conotoxin RIIIJ (kappaM-RIIIJ) selectively inhibits Kv1.2 channels, with an IC50 value of 33 nM [1]. Target: Potassium Channel
| Keywords: | kappaM-RIIIJ |
| MW: | 2807.3 D |
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CRAMP (140-173) (mouse)
Item number: TGM-T80465-50mg
Description: CRAMP (140-173) (mouse), the ortholog of the human LL-37 antimicrobial peptide, inhibits LPS-induced responses and does not colocalize with TLR3 in BEAS-2B cells [1].
| MW: | 3878.61 D |
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kappa-Bungarotoxin
Item number: TGM-T80466-50mg
Description: kappa-Bungarotoxin (kappa-Bgt) is a selective, potent antagonist of alpha3beta2 neuronal nicotinic acetylcholine receptors, characterized by slow reversibility and an IC50 of 2.30 nM [1].
| Keywords: | kappa-Bgt |
| CAS | 124511-67-7 |
| MW: | 7265.22 D |
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