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Palicourein
Item number: TGM-T80415-50mg
Description: Palicourein, a 37-amino-acid cyclic polypeptide, inhibits the in vitro cytopathic effects of HIV-1RF infection in CEM-SS cells with an EC50 value of 0.1 µM and an IC50 value of 1.5 µM [1].
| CAS | 331714-57-9 |
| MW: | 3922.36 D |
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Cacaoidin
Item number: TGM-T80417-50mg
Description: Cacaoidin, a glycosylated lantibiotic extracted from Streptomyces cacaoi, exhibits strong antibacterial effects against Gram-positive pathogens, notably Clostridium difficile [1].
| MW: | 2360.7 D |
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TAT-NEP1-40
Item number: TGM-T80418-50mg
Description: TAT-NEP1-40, a blood-brain barrier (BBB) permeable peptide, confers protection to PC12 cells against oxygen and glucose deprivation (OGD) while promoting neurite outgrowth. Furthermore, it enhances neurologic outcomes post-ischemia by mitigating apoptosis in affected cerebral regions. This compound...
| MW: | 6124.89 D |
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CSD-CH2(1,8)-NH2
Item number: TGM-T80421-50mg
Description: CSD-CH2(1,8)-NH2 is a selective and competitive kappa-opioid receptor (KOR) antagonist with a K i of 6.8 nM. It inhibits calcium mobilization in dorsal root ganglion (DRG) neurons and counters the antinociceptive effect of U50,488, making it useful for research into neuropsychiatric disorders [1]....
| MW: | 1693.09 D |
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Phoenixin-14
Item number: TGM-T80422-50mg
Description: Phoenixin-14 (PNX-14), an active endogenous isoform, induces an anxiolytic effect by activating the AHA GnRH system in mice and protects against ischemia/reperfusion-induced cytotoxicity in microglia [1] [2]. Target: GNRH Receptor
| Keywords: | PNX-14 |
| CAS | 1415039-79-0 |
| MW: | 1583.78 D |
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Phoenixin-20
Item number: TGM-T80423-50mg
Description: Phoenixin-20 (PNX-20) is a vertebrate bioactive peptide with hormone-like actions, stimulating the hypothalamo-pituitary-gonadal axis to regulate mammalian reproduction, enhancing neuronal mitochondrial biogenesis via the CREB-PGC-1alpha pathway, and possessing an anxiolytic effect [1] [2] [3]. Target:...
| Keywords: | PNX-20 |
| CAS | 1415039-77-8 |
| MW: | 2181.45 D |
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Jingzhaotoxin-V
Item number: TGM-T80425-50mg
Description: Jingzhaotoxin-V, a 29-residue polypeptide from Chilobrachys jingzhao spider venom, selectively inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons, with IC50 values of 27.6 nM and 30.2 nM, respectively. Furthermore, it suppresses Kv4.2 potassium...
| MW: | 3605.36 D |
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Jingzhaotoxin-IX
Item number: TGM-T80426-50mg
Description: Jingzhaotoxin-IX is a C-terminally amidated peptide neurotoxin consisting of 35 amino acid residues. It inhibits both tetrodotoxin-resistant and tetrodotoxin-sensitive isoforms of voltage-gated sodium channels, as well as the Kv2.1 channel. However, Jingzhaotoxin-IX does not affect the delayed rectifier...
| MW: | 3953.51 D |
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Jingzhaotoxin-II
Item number: TGM-T80427-50mg
Description: Jingzhaotoxin-II, a neurotoxin composed of 32 amino acid residues featuring two acidic and two basic residues, selectively inhibits voltage-gated sodium channels (VGSC), notably slowing the rapid inactivation of TTX-resistant (TTX-R) VGSC in cardiac myocytes, with an IC50 of 0.26 µM [1]. Target: Sodium...
| MW: | 3561.08 D |
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Jingzhaotoxin-34
Item number: TGM-T80428-50mg
Description: Jingzhaotoxin-34, a 35-residue neurotoxic polypeptide, selectively inhibits tetrodotoxin-sensitive (TTX-S) sodium currents in rat dorsal root ganglion neurons with an IC50 of approximately 85 nM and exerts negligible influence on tetrodotoxin-resistant (TTX-R) sodium currents [1]. Target: Sodium Channel
| MW: | 3561.08 D |
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pi-TRTX-Hm3a
Item number: TGM-T80429-50mg
Description: pi-TRTX-Hm3a, a 37-amino acid peptide derived from the venom of the Togo starburst tarantula (Heteroscodra maculata), selectively inhibits the acid-sensing ion channel 1a (ASIC1a) in a pH-dependent manner, with an inhibitory concentration half-max (IC50) of 1-2 nM, and also potentiates the activity of...
| MW: | 4287.03 D |
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delta-Theraphotoxin-Hm1b
Item number: TGM-T80430-50mg
Description: delta-Theraphotoxin-Hm1b, a 42-amino acid peptide derived from the Togo starburst tarantula (Heteroscodra maculata) venom, selectively inhibits the inactivation of NaV1.1 channels without affecting NaV1.7 channels [1]. Target: Sodium Channel
| MW: | 3895.38 D |
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