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Stromatoxin 1
Item number: TGM-T80172-50mg
Description: Stromatoxin 1, a peptide isolated from tarantulas, acts as an inhibitor of various potassium channels, including K(V)2.1, K(V)2.2, K(V)4.2, and K(V)2.1/9.3. It selectively targets K(V)2.1 and K(V)2.2 channel subunits, which are crucial in counteracting myogenic and neurogenic contractions of rat urinary...
| CAS | 741738-59-0 |
| MW: | 3791.31 D |
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BDS-I
Item number: TGM-T80173-50mg
Description: BDS-I, a marine toxin derived from Anemonia sulcata, functions as a selective inhibitor of the potassium channel, specifically targeting Kv3.4. It impedes the Abeta1-42-induced augmentation of Kv3.4 activity, caspase-3 activation, and distortion of nuclear morphology in NGF-differentiated PC-12 cells....
| CAS | 207621-38-3 |
| MW: | 4708.34 D |
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BmP02
Item number: TGM-T80174-50mg
Description: BmP02, a compound isolated from Chinese scorpion (Buthus martensi Karsch) venom, acts as a selective Kv1.3 channel blocker and a highly-selective Kv4.2 modulator. It delays Kv4.2 inactivation in HEK293T cells, exhibiting an EC50 of approximately 850 nM, and inhibits the transient outward potassium...
| MW: | 2949.35 D |
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Conopeptide rho-TIA
Item number: TGM-T80175-50mg
Description: Conopeptide rho-TIA, a peptide from Conus tulipa venom, acts as a selective, noncompetitive inhibitor at the human alpha1B-Adrenergic Receptor and as a competitive inhibitor at the alpha1A and alpha1D-Adrenergic Receptors. Binding to these subtypes, conopeptide rho-TIA may inform the creation of new...
| CAS | 381725-58-2 |
| MW: | 2390.88 D |
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Crotamine
Item number: TGM-T80176-50mg
Description: Crotamine, a 42 amino acid toxin featuring three disulfide bridges, functions as a Na+ channel modulator with analgesic properties. This compound interacts with lipid membranes and exhibits myonecrotic activity, and can be isolated from the venom of Crotalus durissus terrificus [1] [2]. Target: Sodium...
| MW: | 4883.73 D |
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Phlotoxin-1
Item number: TGM-T80177-50mg
Description: Phlotoxin-1 (PhlTx1), a 34-amino acid peptide featuring three disulfide bridges, is derived from the Phlogiellus genus spider and acts as an antinociceptive agent by inhibiting the NaV1.7 channel [1] [2]. Target: Sodium Channel
| Keywords: | PhlTx1 |
| MW: | 4058.64 D |
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Dc1a
Item number: TGM-T80178-50mg
Description: Dc1a, a toxin isolated from the desert bush spider Diguetia canities [1], potently facilitates the opening of the German cockroach Na v channel (BgNa v 1). Target: Sodium Channel
| MW: | 6397.22 D |
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Maurotoxin
Item number: TGM-T80180-50mg
Description: Maurotoxin, a 34-residue peptide featuring four disulfide bridges, is extracted from the chactoid scorpion (Scorpio maurus) and known to impede Shaker potassium channels (ShB) K+ flow, exhibiting an IC50 of 2 nM [1] [2]. Target: Potassium Channel
| CAS | 188240-41-7 |
| MW: | 3612.19 D |
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GrTx1
Item number: TGM-T80179-50mg
Description: GrTx1, a peptide toxin derived from Grammostola rosea spider venom, selectively inhibits sodium channels Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6, and Nav1.7, with IC50 values of 0.63 µM, 0.23 µM, 0.77 µM, 1.29 µM, 0.63 µM, and 0.37 µM, respectively [2]. This compound has applications in neurological...
| MW: | 3697.43 D |
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Muscarinic toxin 7
Item number: TGM-T80183-50mg
Description: Muscarinic toxin 7 (MT7) is a peptide exhibiting selective, noncompetitive antagonistic activity at the muscarinic M1 receptor [1].
| MW: | 7472.42 D |
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GsAF-II
Item number: TGM-T80184-50mg
Description: GsAF-II is a peptide toxin that selectively blocks hERG1 subtype potassium channels through a voltage-dependent mechanism and impedes Nav1.x subtype sodium channels [1]. Target: Sodium Channel
| MW: | 3979.7 D |
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Huwentoxin I
Item number: TGM-T80185-50mg
Description: Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels. It effectively blocks sodium channels in rat hippocampus and cockroach dorsal unpaired median (DUM) neurons, with IC50 values of 66.1 nM and 4.80 nM, respectively [1]. Target: Calcium Channel
| Keywords: | HWTX-I |
| CAS | 769973-37-7 |
| MW: | 3750.36 D |
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