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Demoxytocin
Item number: TGM-T76049-50mg
Description: Demoxytocin, an analog of oxytocin and a heterodetic cyclic peptide, enhances cell membrane permeability to elevate calcium ion levels in smooth muscle cells, thereby augmenting contraction, including the smooth muscles of the uterus. This compound mirrors oxytocin's function and is utilized in studies...
| Application: | Targets oxytocin receptor (OXTR) |
| CAS | 113-78-0 |
| MW: | 992.17 D |
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NFF-3 TFA
Item number: TGM-T76051-50mg
Description: NFF-3 TFA, a selective matrix metalloproteinase (MMP) substrate, specifically interacts with MMP-3 and MMP-10 for hydrolysis. Additionally, it undergoes cleavage by trypsin, hepatocyte growth factor activator, and factor Xa. When labeled with the CyDye pair, Cy3/Cy5Q, NFF-3 TFA generates fluorescence in...
| MW: | 1789.87 D |
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ELA-32(human) TFA
Item number: TGM-T76052-50mg
Description: ELA-32(human) TFA is a potent apelin receptor agonist with high affinity, demonstrating an IC50 of 0.27 nM and a Kd of 0.51 nM. This compound does not bind to GPR15 or GPR25. It activates the PI3K/AKT signaling pathway, facilitating self-renewal of human embryonic stem cells (hESCs) through cell-cycle...
| MW: | 4081.84 D |
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ELA-11(human) TFA
Item number: TGM-T76053-50mg
Description: ELA-11(human) TFA, a bioactive fragment of ELA-32, acts as a high-affinity apelin receptor agonist (K i =14 nM). It effectively inhibits forskolin-induced cAMP production and promotes beta-arrestin recruitment in vitro, highlighting its significant agonistic activity.
| MW: | 1397.58 D |
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SAHM1 TFA
Item number: TGM-T76054-50mg
Description: SAHM1 TFA is a chemical compound that acts as a Notch pathway inhibitor by stabilizing a hydrocarbon-stapled alpha helical peptide. It specifically targets the protein-protein interface, effectively preventing the assembly of the Notch complex.
| MW: | 2310.6 D |
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Glepaglutide
Item number: TGM-T76056-50mg
Description: Glepaglutide (ZP1848), a long-acting glucagon-like peptide-2 (GLP-2) analogue, functions as a potent GLP-2 receptor (GLP-2R) agonist, effectively reducing fecal output and enhancing intestinal absorption while alleviating small intestine inflammation. It holds potential for researching inflammatory...
| CAS | 914009-86-2 |
| MW: | 4316.08 D |
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Glepaglutide acetate
Item number: TGM-T76057-50mg
Description: Glepaglutide (ZP1848) acetate is a long-acting glucagon-like peptide-2 (GLP-2) analogue and a potent GLP-2 receptor (GLP-2R) agonist. It significantly reduces fecal output and enhances intestinal absorption while also mitigating inflammation in the small intestine. Glepaglutide acetate is relevant in...
| MW: | 4376.13 D |
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Tat-beclin 1 TFA
Item number: TGM-T76058-50mg
Description: Tat-beclin 1 TFA, a peptide derived from a segment of the autophagy protein beclin 1, effectively induces autophagy and interacts with the autophagy negative regulator GAPR-1 (GLIPR2). It reduces the accumulation of polyglutamine expansion protein aggregates and limits the in vitro replication of...
| MW: | 3855.12 D |
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NLS-StAx-h TFA
Item number: TGM-T76060-50mg
Description: NLS-StAx-h TFA is a selective and cell-permeable stapled peptide that inhibits Wnt signaling with an IC50 value of 1.4 µM, effectively suppressing beta-catenin-transcription factor interactions and demonstrating anti-proliferative effects on cancer cells [1] [2].
| MW: | 3559.28 D |
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Parathyroid hormone (1-34) (rat) acetate
Item number: TGM-T76061-50mg
Description: Parathyroid hormone (1-34) (rat) (acetate) is a variant that enhances the structure of cortical and cancellous bones and is utilized in osteoporosis research [1] [2].
| MW: | 4117.76 D |
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Beta-defensin 1, pig
Item number: TGM-T76063-50mg
Description: Beta-defensin 1, pig, is an antimicrobial peptide predominantly located in the tongue mucosa of pigs. It exhibits activity against a variety of bacteria including Escherichia coli, Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus, Bordetella pertussis, and the fungus Candida...
| MW: | 7410.9 D |
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Beta-defensin 1, pig TFA
Item number: TGM-T76063L-50mg
Description: Beta-defensin 1, pig TFA, an antimicrobial peptide predominantly located in the tongue mucosa of pigs, exhibits activity against a diverse range of bacteria including Escherichia coli, Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus, Bordetella pertussis, and the fungus Candida...
| MW: | 7524.92 D |
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