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Galanin (1-29)(rat, mouse) TFA
Item number: TGM-T75818-50mg
Description: Galanin (1-29)(rat, mouse) TFA acts as a non-selective agonist for galanin receptors, exhibiting affinities (Kis) of 0.98 nM for GAL1, 1.48 nM for GAL2, and 1.47 nM for GAL3, respectively, and possesses an anticonvulsant effect [1] [2].
| MW: | 3278.47 D |
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M1145 TFA
Item number: TGM-T75819-50mg
Description: M1145 TFA, a chimeric peptide, acts as a selective agonist for the galanin receptor type 2 (GAL2), demonstrating a binding affinity (K i) of 6.55 nM. It exhibits significantly greater selectivity for GAL2, with over 90-fold and 76-fold higher affinity compared to GAL1 (K i = 587 nM) and GalR3 (K i = 497...
| MW: | 2888.25 D |
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TAT-Gap19 TFA
Item number: TGM-T75821-50mg
Description: TAT-Gap19 TFA, a Cx mimetic peptide and specific connexin43 hemichannel (Cx43 HC) inhibitor, does not inhibit corresponding Cx43 gap junction channels (GJCs). It crosses the blood-brain barrier and has shown efficacy in alleviating liver fibrosis in mice [1] [2] [3].
| MW: | 2817.27 D |
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GLP-1(9-36)amide TFA
Item number: TGM-T75822-50mg
Description: GLP-1(9-36)amide TFA, a predominant metabolite of glucagon-like peptide-1-(7-36)amide synthesized through dipeptidyl peptidase-4 (DPP-4) activity, functions as an antagonist to the human pancreatic GLP-1 receptor [1] [2].
| MW: | 3203.43 D |
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GLP-2(rat) TFA
Item number: TGM-T75823-50mg
Description: GLP-2(rat) TFA, an intestinal growth factor, promotes cell proliferation and prevents apoptosis. Additionally, it increases mucosal mass and function in the residual small intestine following massive small bowel resection (MSBR), as documented in references [1] [2].
| MW: | 3910.16 D |
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Bay 55-9837 TFA
Item number: TGM-T75825-50mg
Description: Bay 55-9837 TFA, a potent and highly selective VPAC2 agonist with a dissociation constant (Kd) of 0.65 nM, represents a potential research therapy for type 2 diabetes [1].
| MW: | 3456.22 D |
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D[LEU4,LYS8]-VP TFA
Item number: TGM-T75826-50mg
Description: D[LEU4,LYS8]-VP TFA is a selective agonist for the vasopressin V1b receptor, with Ki values of 0.16 nM for rat, 0.52 nM for human, and 1.38 nM for mouse V1b receptors. This compound exhibits limited antidiuretic, vasopressor, and oxytocic activities in vitro [1] [2].
| MW: | 1140.25 D |
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UFP-803 TFA
Item number: TGM-T75827-50mg
Description: UFP-803 TFA, a potent ligand for the urotensin-II receptor (UT), exhibits minimal residual agonist activity, rendering it a valuable asset for exploring the UT system's function in physiology and pathology [1].
| MW: | 1175.25 D |
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[Orn5]-URP TFA
Item number: TGM-T75828-50mg
Description: [Orn5]-URP TFA acts as a potent and selective antagonist exclusively targeting the Urotensin-II receptor (UT), devoid of any agonist activity, and demonstrates a significant inhibitory efficiency with a pEC50 value of 7.24 [1] [2].
| MW: | 1117.22 D |
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L-R4W2 TFA
Item number: TGM-T75830-50mg
Description: L-R4W2 TFA acts as a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), demonstrating significant inhibitory activity with an IC50 value of 0.1 µM. This compound potentially offers powerful analgesic properties [1] [2].
| MW: | 1128.22 D |
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NTR 368 TFA
Item number: TGM-T75831-50mg
Description: NTR 368 TFA, a peptide derived from the p75 neurotrophin receptor (p75NTR) and corresponding to residues 368-381 of the human receptor, exhibits a helix-forming propensity in the presence of micellar lipid. It is a potent inducer of neural apoptosis [1].
| MW: | 1679.88 D |
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Cyclotraxin B TFA
Item number: TGM-T75832-50mg
Description: Cyclotraxin B TFA, a cyclic peptide, is a highly potent and selective non-competitive inhibitor of TrkB, effectively impeding BDNF-triggered TrkB activity without altering BDNF binding affinity, with an IC50 of 0.30 nM. It crosses the blood-brain barrier, demonstrating analgesic and anxiolytic-like...
| MW: | 1314.39 D |
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