Tumor Necrosis Factor Receptor Superfamily Member 9, active (TNFRSF9), Recombinant, Human

Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. Biological Activity: Fully biologically active when compared to standard. The biological activity is determined by its inhibitory effect of IL-8 production using human peripheral blood mononuclear cells. About 90 % of inibition was seen using a concentration of 1 ug for both 4-1BB Ligand and 4-1BB Receptor. Sequence: ERTRSLQDPC SNCPAGTFCD NNRNQICSPC PPNSFSSAGG QRTCDICRQC KGVFRTRKEC SSTSNAECDC TPGFHCLGAG CSMCEQDCKQ GQELTKKGCK DCCFGTFNDQ KRGICRPWTN CSLDGKSVLV NGTKERDVVC GPSPADLSPG ASSVTPPAPA REPGHS, Molecular Weight: 17.7kD, PubMed ID: 8088337, 8262389, 7622190, 16710414, 15489334, 15340161, 9418902, 9607925, 11804328, 16959974, Gene Name: TNFRSF9,CD137,ILA, Swiss Prot: Q07011, Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.