Transforming Growth Factor-Beta 2, HEK, human recombinant (rHuTGF-b2-HEK)

Human recombinant TGF-b 2 produced in HEK cells is a non-glycosylated homodimer, having a total molecular weight of 25kDa. TGFB2 is a 27.08 kDa protein having two identical 118 amino acid peptide chains linked by a single disulfide bond. TGFB2 is part of a family of five related cytokines that have an extensive variation of normal and neoplastic cells, indicating the importance of these homo-dimmer proteins as multi-functional regulators of cellular activity. The three mammalian isoforms of TGF-beta (TGFb1, TGFb2 and TGFb3) signal through the same receptor and stimulate similar biological responses. They are involved in physiological processes as embryogenesis, tissue remodelling and wound healing.