Thymic Stromal Lymphopoietin/TSLP Protein(C-Fc) (recombinant mouse)

Protein Construction: Recombinant Mouse Thymic stromal lymphopoietin is produced by our Mammalian expression system and the target gene encoding Tyr20-Glu140 is expressed with a Fc tag at the C-terminus. Sequence: Tyr20-Glu140. Fusion tag: C-Fc Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 42-58 kDa. Protein function: Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells such as fibroblasts, epithelial cells and different types of stromal or stromal-like cells. These cells are located in regions where TSLP activity is required. Protein function: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. [The UniProt Consortium]