Recombinant Murine FGF

Murine basic fibroblast growth factor (bFGF or FGF-2) is a multifunctional protein crucial in mouse cellular biology. Expressed across various tissues, it lacks a typical secretory signal peptide and exists in multiple isoforms through alternative translation start sites. bFGF plays pivotal roles in cell proliferation, migration, differentiation, and angiogenesis, with significant involvement in embryonic stem cell maintenance and tissue development. It's expression can be modulated by factors like stem cell factor and transforming growth factor-beta, and it demonstrates important functions in both normal physiological processes and pathological conditions, such as cancer cell progression. The protein's diverse capabilities make it a key molecule in understanding mouse cellular mechanisms and potential therapeutic interventions.