Recombinant Human Growth Hormone

Human Growth Hormone (GH) is a member of a family of growth factors that includes prolactin, placental lactogens, proliferins, and somatolactin. It is synthesized primarily by somatotropes in the anterior pituitary and is stored in secretary granules. The pulsatile release of GH into circulation is regulated by the concerted actions of the hypothalamic hormones-GH-releasing hormone (GHRH) and somatostatin (SST) - as well as by signals from the periphery - ghrelin and leptin.4 The human GH cDNA encodes a 217 amino acid (aa) residue precursor protein with a 26 aa putative signal peptide. By alternative splicing, at least four alphasoforms of GH have been identified. Shipping and Storage rhGH is shipped on gel pack. Upon receipt, store at -20oC after receiving. Upon reconstitution, store at 2-8 oC for up to one week. For maximal stability, aliquot and store at -20oC. Avoid repeated freeze/ thaw cycles. Usage rhGH is for research use only. rhGH is not approved for human or animal use, or for application in clinical or in vitro diagnostic procedures