Recombinant Human Gankyrin/PSDM10 Protein (RPES4761)

Recombinant Human Gankyrin/PSDM10 Protein (RPES4761)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-RPES4761.10 10 µg - - -

9 - 20 business days*

171.00€
 
Human Gankyrin/PSDM10 Recombinant Protein (RPES4761) is a highly pure recombinant protein... more
Product information "Recombinant Human Gankyrin/PSDM10 Protein (RPES4761)"
Human Gankyrin/PSDM10 Recombinant Protein (RPES4761) is a highly pure recombinant protein developed by Assay Genie for use in a range of applications Protein function: Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pathway, leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis. [The UniProt Consortium]
Keywords: PSMD10, Gankyrin, p28(GANK), 26S proteasome regulatory subunit p28, 26S proteasome non-ATPase regulatory subunit 10
Supplier: Assay Genie
Supplier-Nr: RPES4761

Properties

Conjugate: No
Host: E.coli
Species reactivity: human
Format: Highly Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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