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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSH032838.10 | 10 µg | - |
7 - 16 business days* |
212.00€
|
|||
E-PKSH032838.50 | 50 µg | - |
7 - 16 business days* |
622.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Construction: Recombinant Human Osteocrin is produced by our E.coli expression system and... more
Product information "Osteocrin Protein(N-6His) (recombinant human)"
Protein Construction: Recombinant Human Osteocrin is produced by our E.coli expression system and the target gene encoding Val28-Gly133 is expressed with a 6His tag at the N-terminus. Sequence: Val28-Gly133. Fusion tag: N-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 12 kDa. Protein function: Osteocrin is a secreted protein which is primarily expressed in bone and muscle. It is synthesized as a proprotein that undergoes proteolytic processing to generate a mature 50 amino acid C-terminal active peptide.Human Osteocrin proprotein shares 77% and 78% amino acid sequence identity with the rat and mouse protein, respectively. It appears to modulate osteoblastic differentiation. It could also function as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle. Protein function: Hormone that acts as a regulator of dendritic growth in the developing cerebral cortex in response to sensory experience (PubMed:27830782). Induced in the brain following membrane depolarization and inhibits dendritic branching in neurons of the developing cortex (PubMed:27830782). Probably acts by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production. [The UniProt Consortium]
Keywords: | , Recombinant Human Osteocrin Protein(N-6His) |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSH032838 |
Properties
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
MW: | 14.0 kD |
Format: | Lyophilized |
Database Information
UniProt ID : | P61366 | Matching products |
Gene ID | GeneID 344901 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | +4°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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