Nampt (Visfatin/PBEF) (human, rec.) (His) (BULK)

Nampt (Visfatin/PBEF) (human, rec.) (His) (BULK)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-40A-0018AA-C500 500 µg -

3 - 9 business days*

2,585.00€
 
Intracellular human Nampt (visfatin/PBEF) (amino acids 1-491) is fused at the C-terminus to a... more
Product information "Nampt (Visfatin/PBEF) (human, rec.) (His) (BULK)"
Intracellular human Nampt (visfatin/PBEF) (amino acids 1-491) is fused at the C-terminus to a His-tag. Shows adipogenic effects in stimulated differentiating 3T3-L1 cells. Lyophilized. Salt-free. Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Keywords: Pre-B Cell Colony Enhancing Factor 1, PBEF1, Nicotinamide Phosphoribosyltransferase
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-40A-0018AA

Properties

Application: Bioassays
Conjugate: No
Expressed in: E.coli
Origin: Human
MW: 52 kD
Format: Lyophilized

Database Information

KEGG ID : K03462 | Find alternatives
UniProt ID : P43490 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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