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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-RPES6693.20 | 20 µg | - | - | - |
9 - 20 business days* |
384.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Multifunctional cytokine mainly produced by T-cells that plays a regulatory... more
Product information "Mouse IL-24 Recombinant Protein (N-His) (active)"
Protein function: Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis (PubMed:31907348, PubMed:35148201). Possesses antiviral functions and induces the type I interferon response during influenza infection. Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1. In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1. Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal (PubMed:31907348). In addition, acts as a quality control mechanism for the ubiquitin proteasome system by alerting the cell to proteasome dysfunction through activation of PKR/EIF2AK2 (PubMed:35148201). [The UniProt Consortium]
| Keywords: | Mda7, Il24, IL-24, MDA-7, Interleukin-24, Th2-specific cytokine FISP, IL-4-induced secreted protein, Melanoma differentiation-associated gene 7 protein |
| Supplier: | Assay Genie |
| Supplier-Nr: | RPES6693 |
Properties
| Conjugate: | No |
| Host: | E.coli |
| Species reactivity: | mouse |
| Format: | Lyophilized |
Database Information
| KEGG ID : | K22668 | Matching products |
| UniProt ID : | Q925S4 | Matching products |
| Gene ID : | GeneID 93672 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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