MESDC2, aa34-234, Recombinant, Human (Mesoderm Development Candidate 2, BOCA, KIAA0081, LDLR Chapero

MESDC2, also known as Mesoderm development candidate 2, is required for formation of the primitive streak and mesoderm during embryogenesis. This protein binds to the Wnt co-receptors LRP5 and LRP6 in the endoplasmic reticulum and is required for their proper folding and cell surface expression. Source: Recombinant corresponding to human MESDC2, fused to His-tag at N-terminus, expressed in E. coli. Molecular Weight: ~24.9kD, Sequences of Amino Acids: MGSSHHHHHH SSGLVPRGSH MAEGSPGTPD ESTPPPRKKK KDIRDYNDAD MARLLEQWEK DDDIEEGDLP EHKRPSAPVD FSKIDPSKPE SILKMTKKGK TLMMFVTVSG SPTEKETEEI TSLWQGSLFN ANYDVQRFIV GSDRAIFMLR DGSYAWEIKD FLVGQDRCAD VTLEGQVYPG , KGGGSKEKNK TKQDKGKKKK EGDLKSRSSK EENRAGNKRE DL, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.