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Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated polypeptide chain containing 184 amino acids. The ED50 as determined by the dose-dependant stimulation of murine 7TD1 cells is < 0.1 ng/ml.
Keywords: | IFN-b2, B cell differentiation factor, BCDF, BSF-2, HPGF, HSF, MGI-2, B-cell stimulatory factor 2, Interferon beta-2, Hybridoma growth factor, CTL differentiation factor, CDF, IL-6, HGF |
Supplier: | Biomol GmbH |
Supplier-Nr: | 50436.1 |
Properties
Application: | Cell culture |
Conjugate: | No |
Expressed in: | E.coli |
Origin: | Human |
MW: | 21000 D |
Purity: | >97% |
Database Information
KEGG ID : | K05405 | Find alternatives |
UniProt ID : | P05231 | Find alternatives |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Our products are for laboratory research use only: Not for administration to humans!