Interleukin-31, mouse recombinant (rmIL-31)

Interleukin-31, mouse recombinant (rmIL-31)
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
97509.2 2 µg - -

3 - 10 business days*

70.00€
97509.10 10 µg - -

3 - 10 business days*

180.00€
97509.1 1 mg - -

3 - 10 business days*

-
 
Mouse recombinant IL31 produced in E.coli is a single, non-glycosylated, polypeptide chain... more
Product information "Interleukin-31, mouse recombinant (rmIL-31)"

Mouse recombinant IL31 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 141 amino acids and having a molecular mass of 15.7 kDa. IL-31 produced by activated Th2-type T cells, cooperates with a heterodimeric receptor consisting of IL-31 Receptor Anatagonist and Onconstatin-M Receptor that is continuesly expressed on epithelial cells and keratinocytes. IL-31 plays a role in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma. IL-31 is involved in the itching sensation and endorses the scratching behavior in NC/Nga mice with atopic dermatitis. IL-31 expression is connectd with CLA(+) T cells and contributes to the development of atopic dermatitis-induced skin inflammation and pruritus. IL-31 is a powerful inducer of proinflammatory mediators in human colonic SEMFs. IL-31 takes part as a proinflammatory cytokine derived from Th2 cells.

Keywords: Interleukin 31, IL31, IL-31.
Supplier: Biomol GmbH
Supplier-Nr: 97509

Properties

Application: Bioassay
Conjugate: No
Expressed in: E.coli
Origin: Mouse
MW: 15700 D
Purity: >97%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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