Interleukin-11

Interleukin-11
Item number Size Datasheet Manual SDS Delivery time Quantity Price
010-001-V49-0100 100 µg - -

6 - 10 business days*

1,303.00€
 
Interleukin-11 purity was determined to be greater than 95% as determined by analysis by... more
Product information "Interleukin-11"
Interleukin-11 purity was determined to be greater than 95% as determined by analysis by UV-Spectroscopy at 280nm and by reducing and non-reducing SDS-pAGE. Protein function: Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:8913282). Also promotes the proliferation of hepatocytes in response to liver damage (PubMed:22253262). Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation, also in the context of various cancers (PubMed:10026196, PubMed:23948300). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3 (PubMed:23948300, PubMed:22253262). [The UniProt Consortium]
Keywords: Il11, IL-11, Interleukin-11
Supplier: Rockland Immunochemicals
Supplier-Nr: 010-001-V49-0100

Properties

Application: Cell culture
Conjugate: No
Host: E.coli
Species reactivity: mouse

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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