IL-7 (human), animal-free recombinant

Product Description: IL-7 is a hematopoietic growth factor with a key impact on early B and T cells. It originates from thymic stromal cells, spleen cells, and keratinocytes. In addition to its primary effects, IL-7 can collaborate with other factors like ConA and IL-2 to stimulate the proliferation of mature T cells. Interestingly, Human and murine IL-7 show cross-species reactivity. Recombinant Human IL-7 is a 17.5 kDa protein comprising 153 amino acid residues. . Amino acid sequence: MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH. Endotoxin concentration: <0.1 EU/µg. Activity: Determined by its ability to stimulate the proliferation of mouse 2E8 cells. The expected ED50 = 0.5 ng/ml, corresponding to a specific activity of > 2 x 10^6 units/mg. Contains no preservative. Protein function: Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. [The UniProt Consortium]