IL-4, equine recombinant (reqIL-4)

Biologically active. Produced in Yeast. Amino acid sequence: GCKYDIT LQEIIKTLNN LTDGKGKNSC MELTVADAFA GPKNTDGKEI CRAAKVLQQL YKRHDRSLIK ECLSGLDRNL KGMANGTCCT VNEAKKSTLK DFLERLKTIM KEKYSKC. Protein function: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. [The UniProt Consortium]